| Derock Electric Company LLC | Construction | $332,675 | $334,807 | 33 | $10.9M | AI Deep Dive |
| Cepal Corporation | Retail Trade | $332,500 | $334,295 | 44 | $6.9M | AI Deep Dive |
| Derock Electric Company LLC | Construction | $330,312 | $332,149 | 34 | $11.2M | AI Deep Dive |
| Medical Arts Allergy, PC | Health Care and Social Assistance | $327,462 | $330,602 | 29 | $9.1M | AI Deep Dive |
| E&g Services, Inc. | Construction | $325,857 | $328,473 | 27 | $8.9M | AI Deep Dive |
| Carlisle Suites 10, LLC | Accommodation and Food Services | $321,235 | $323,955 | 38 | $11.9M | AI Deep Dive |
| Energy Managment Concepts Inc. | Utilities | $314,517 | $317,774 | 9 | N/A | AI Deep Dive |
| Mayapple Bar and Grille INC | Accommodation and Food Services | $311,800 | $314,139 | 40 | $7.1M | AI Deep Dive |
| The Cataract & Laser Surgery Center of Central PA | Health Care and Social Assistance | $310,107 | $311,537 | 26 | <$5M | AI Deep Dive |
| The Cataract & Laser Surgery Center of Central PA | Health Care and Social Assistance | $310,100 | $313,709 | 21 | $6.6M | AI Deep Dive |
| Mildin, Inc. DBA Cardin & Miller Physical Therapy, P.c. | Health Care and Social Assistance | $309,336 | $311,064 | 30 | $8.1M | AI Deep Dive |
| Cepal Corp. | Retail Trade | $306,170 | $307,948 | 43 | $6.7M | AI Deep Dive |
| Young Men's Christian Association of Carlisle | Arts, Entertainment, and Recreation | $303,822 | $305,878 | 154 | N/A | AI Deep Dive |
| Young Men's Christian Association of Carlisle | Health Care and Social Assistance | $303,820 | $307,033 | 135 | N/A | AI Deep Dive |
| A Party of 4 INC | Accommodation and Food Services | $296,772 | $299,886 | 25 | <$5M | AI Deep Dive |
| Carlisle Pediatric Associates | Health Care and Social Assistance | $289,015 | $290,749 | 17 | $5.3M | AI Deep Dive |
| Family Ford of Pennsylvania INC | Retail Trade | $277,600 | $279,836 | 33 | $8.3M | AI Deep Dive |
| Carlisle Country Club | Other Services (except Public Administration) | $271,248 | $274,926 | 59 | N/A | AI Deep Dive |
| Keystone Foundation Repair INC | Construction | $262,447 | $264,396 | 21 | <$5M | AI Deep Dive |
| Elite Plumbing, Heating & Ac, LLC | Construction | $259,300 | $260,748 | 18 | $5.7M | AI Deep Dive |
| Keystone Foundation Repair, Inc. | Construction | $254,102 | $256,365 | 15 | <$5M | AI Deep Dive |
| Stoken Wagner Ophthalmic Associates LLC | Health Care and Social Assistance | $250,040 | $251,888 | 23 | $7.2M | AI Deep Dive |
| Romeo & Juliet Inc. | Accommodation and Food Services | $246,096 | $248,772 | 80 | $14.2M | AI Deep Dive |
| Tuckey Metal Fabricators INC | Manufacturing | $240,142 | $243,353 | 16 | <$5M | AI Deep Dive |
| Tuckey Metal Fabricators INC | Manufacturing | $240,100 | $243,231 | 23 | $5.6M | AI Deep Dive |