| The Palmas Academy INC | Educational Services | $215,000 | $217,664 | 57 | $6.8M |  Research |
| Bb&r LLC | Accommodation and Food Services | $206,700 | $208,853 | 57 | $10.1M | Research |
| Model Offset Printing Corp. | Manufacturing | $196,905 | $197,890 | 28 | $27.8M | Research |
| Model Offset Printing, Corp. | Manufacturing | $196,905 | $198,814 | 28 | $27.8M | Research |
| C & N Del Este Trading Corporation | Unknown | $188,200 | $189,915 | 40 | N/A | Research |
| Easy Energy Group LLC | Other Services (except Public Administration) | $185,800 | $186,419 | 18 | <$5M | Research |
| Easy Energy Group LLC | Other Services (except Public Administration) | $185,800 | $187,813 | 19 | <$5M | Research |
| Melvin Rodriguez DBA None | Health Care and Social Assistance | $181,670 | $183,320 | 36 | $11.3M | Research |
| Isopharm Services INC | Construction | $166,600 | $202,318 | 41 | $13.5M | Research |
| Orvis V Corporation | Professional, Scientific, and Technical Services | $160,700 | $162,722 | 17 | <$5M | Research |
| Pennock Growers, Inc. | Administrative and Support and Waste Management | $159,700 | $161,865 | 27 | $5.8M | Research |
| Osnet Wireless Corporation | Information | $159,300 | $160,729 | 31 | $5.2M | Research |
| Aluminios De Puerto Rico LLC | Manufacturing | $154,583 | $156,043 | 53 | $13.9M | Research |
| Gumet INC | Health Care and Social Assistance | $149,000 | $149,915 | 27 | $8.5M | Research |
| Aluminios De Puerto Rico LLC | Manufacturing | $148,939 | $149,714 | 53 | $13.9M | Research |
| Gumet INC | Unknown | $144,900 | $146,051 | 31 | N/A | Research |
| P B V Corporation | Unknown | $143,600 | $144,988 | 42 | N/A | Research |
| Instituto De Radioterapia Avanzada Del Este Psc | Health Care and Social Assistance | $140,500 | $141,979 | 19 | $6.0M | Research |
| Bb&r LLC | Accommodation and Food Services | $139,200 | $140,816 | 53 | $9.4M | Research |
| Pavarini Construction & Development, LLC | Construction | $139,200 | $140,859 | 36 | $41.0M | Research |
| Pdm Utility Corporation | Utilities | $134,500 | $135,770 | 15 | N/A | Research |
| Instituto De Radioterapia Avanzada Del Este Psc | Health Care and Social Assistance | $134,500 | $135,673 | 20 | $6.3M | Research |
| Colegio San Benito, Humacao, Puerto Rico, Inc. | Educational Services | $132,100 | $132,746 | 45 | N/A | Research |
| Industrial Technical College, Inc. | Educational Services | $131,800 | $132,774 | 33 | <$5M | Research |
| Industrial Technical College INC | Educational Services | $131,800 | $132,558 | 23 | <$5M | Research |