| Lowcountry Therapy Center LLC | Health Care and Social Assistance | $493,815 | $495,982 | 38 | $10.3M |  AI Deep Dive |
| Superior Heating and Air Inc. | Construction | $487,100 | $490,807 | 53 | $16.8M | AI Deep Dive |
| Cbm Enterprises, LLC | Accommodation and Food Services | $479,400 | $484,575 | 141 | $25.0M | AI Deep Dive |
| Sungate Medical Group LLC | Health Care and Social Assistance | $473,400 | $476,661 | 40 | $12.6M | AI Deep Dive |
| Sungate Medical Group LLC | Health Care and Social Assistance | $472,700 | $475,707 | 52 | $16.3M | AI Deep Dive |
| Team Vaden Imports, Inc. | Retail Trade | $466,567 | $469,613 | 31 | $7.8M | AI Deep Dive |
| May River Dermatology, LLC | Health Care and Social Assistance | $449,000 | $453,564 | 48 | $15.1M | AI Deep Dive |
| Okatie Ale House | Accommodation and Food Services | $437,800 | $440,536 | 69 | $12.3M | AI Deep Dive |
| Court Atkins Architects Inc. | Professional, Scientific, and Technical Services | $437,700 | $440,071 | 27 | $8.4M | AI Deep Dive |
| Security Now Usa, Llc-Sba Small 7a Term | Unknown | $435,670 | $269,676 | 1 | N/A | AI Deep Dive |
| Boys & Girls Clubs of the Lowcountry, Inc. | Health Care and Social Assistance | $430,688 | $434,109 | 120 | N/A | AI Deep Dive |
| St. Gregory the Great Catholic Church | Other Services (except Public Administration) | $377,110 | $0 | 43 | N/A | AI Deep Dive |
| Jameson's Carolina Inc. | Accommodation and Food Services | $349,404 | $352,733 | 48 | $8.5M | AI Deep Dive |
| Justco Inc. | Accommodation and Food Services | $338,500 | $340,672 | 49 | $8.7M | AI Deep Dive |
| Hospice Care of the Lowcountry, Inc. | Health Care and Social Assistance | $335,972 | $340,032 | 27 | N/A | AI Deep Dive |
| Bluffton Veterinary Hospital | Professional, Scientific, and Technical Services | $334,200 | $336,223 | 36 | $5.0M | AI Deep Dive |
| Palmetto Pediatrics of the Lowcountry, LLC | Health Care and Social Assistance | $317,817 | $320,218 | 26 | $8.2M | AI Deep Dive |
| Okatie Ale House, Inc. | Accommodation and Food Services | $312,700 | $315,254 | 78 | $13.8M | AI Deep Dive |
| Maginnis Orthodontics INC | Health Care and Social Assistance | $311,000 | $313,804 | 48 | $11.1M | AI Deep Dive |
| Southern Barrel Inc. | Accommodation and Food Services | $299,141 | $303,005 | 42 | $7.5M | AI Deep Dive |
| Manna Inc. of the Low Country | Accommodation and Food Services | $291,300 | $294,301 | 78 | $13.8M | AI Deep Dive |
| Jrcl Inc. | Construction | $289,500 | $291,985 | 31 | $10.6M | AI Deep Dive |
| Vaux Marscher Berglind, P.a. | Professional, Scientific, and Technical Services | $286,152 | $288,347 | 21 | $5.1M | AI Deep Dive |
| Savannah Staffing, Inc. | Administrative and Support and Waste Management | $282,900 | $285,822 | 36 | $5.7M | AI Deep Dive |
| Savannah Staffing Inc. | Administrative and Support and Waste Management | $282,900 | $284,504 | 36 | $5.7M | AI Deep Dive |