| Dewberry 334 Meeting Street LLC | Accommodation and Food Services | $1,464,447 | $1,484,669 | 16 | $5.0M |  Research |
| Crescent Homes Sc, LLC | Construction | $1,445,800 | $1,459,070 | 80 | $24.3M | Research |
| Buck Management Corp | Real Estate and Rental and Leasing | $1,408,570 | $1,422,424 | 271 | $40.6M | Research |
| Pearlz Holdings INC | Accommodation and Food Services | $1,407,800 | $1,419,178 | 163 | $28.9M | Research |
| South Carolina Aquarium | Arts, Entertainment, and Recreation | $1,401,690 | $1,412,942 | 109 | $16.6M | Research |
| Southern Lumber & Millwork Corp | Retail Trade | $1,373,715 | $1,385,006 | 120 | $24.8M | Research |
| Ncgs, Inc. | Manufacturing | $1,294,905 | $1,304,725 | 78 | $77.4M | Research |
| Ncgs INC | Professional, Scientific, and Technical Services | $1,277,053 | $1,286,879 | 65 | $13.5M | Research |
| Charleston School of Law LLC | Educational Services | $1,264,900 | $1,276,405 | 68 | $8.2M | Research |
| Young Clement Rivers LLP | Professional, Scientific, and Technical Services | $1,261,500 | $1,270,155 | 83 | $20.2M | Research |
| Vikor Scientific, LLC | Health Care and Social Assistance | $1,254,260 | $1,700,000 | 167 | $38.7M | Research |
| Pirate Services | Accommodation and Food Services | $1,233,941 | $1,246,010 | 101 | $31.6M | Research |
| Advantage Media Group INC | Information | $1,228,060 | $1,244,264 | 65 | $10.9M | Research |
| Mankiewicz Coatings LLC | Manufacturing | $1,221,263 | $1,228,862 | 80 | $79.3M | Research |
| Halls Chophouse Columbia LLC | Accommodation and Food Services | $1,204,759 | $1,222,964 | 138 | $24.5M | Research |
| Olde Pink House LLC the | Accommodation and Food Services | $1,199,516 | $1,208,291 | 165 | $29.3M | Research |
| Trust a Thomas Parsell Revocable Trust | Accommodation and Food Services | $1,177,316 | $1,190,659 | 77 | $13.7M | Research |
| Cape Romain Contractors | Construction | $1,167,400 | $1,174,858 | 119 | $36.9M | Research |
| Home Team Management Company LLC | Accommodation and Food Services | $1,157,730 | $1,167,056 | 52 | $9.2M | Research |
| Rhtn LLC | Accommodation and Food Services | $1,144,052 | $1,155,210 | 122 | $38.1M | Research |
| Van Smith Company | Manufacturing | $1,137,195 | $1,146,012 | 76 | $75.4M | Research |
| Van Smith Company INC | Manufacturing | $1,137,192 | $1,147,162 | 69 | $68.4M | Research |
| Grace Hospitality LLC | Accommodation and Food Services | $1,121,400 | $1,135,195 | 152 | $47.5M | Research |
| Wellmore of Daniel Island, LLC | Health Care and Social Assistance | $1,117,977 | $1,127,356 | 185 | $31.5M | Research |
| Baker Cadillac LLC | Retail Trade | $1,114,799 | $1,128,270 | 75 | $18.9M | Research |