| Suminoe Textiles of America Corporation | Manufacturing | $3,713,223 | $3,756,647 | 309 | $109.1M |  Research |
| Hamrick Mills INC | Manufacturing | $3,437,500 | $3,476,649 | 403 | $142.2M | Research |
| Limestone College | Administrative and Support and Waste Management | $3,122,100 | $3,157,657 | 409 | N/A | Research |
| Limestone University | Educational Services | $2,000,000 | $2,016,778 | 288 | N/A | Research |
| Carolina Cotton Works Inc. | Manufacturing | $1,568,585 | $1,576,646 | 146 | $51.5M | Research |
| Carolina Cotton Works, INC | Manufacturing | $1,568,585 | $1,585,752 | 102 | $36.0M | Research |
| Keystone Constructors, Inc. | Construction | $1,432,860 | $1,446,751 | 89 | $28.4M | Research |
| Randolph Trucking, LLC | Transportation and Warehousing | $1,043,198 | $1,053,340 | 79 | $21.1M | Research |
| Broad River Electric Cooperative, Inc. | Utilities | $1,000,000 | $992,114 | 50 | N/A | Research |
| Blue Ridge in Brookview House LLC | Health Care and Social Assistance | $924,500 | $936,177 | 127 | $21.6M | Research |
| Hessamerica | Manufacturing | $831,645 | $839,665 | 66 | $17.3M | Research |
| Specialized Riggers & Riggers INC | Manufacturing | $728,519 | $736,363 | 44 | $10.8M | Research |
| Specialized Riggers and Erectors INC | Construction | $666,300 | $673,985 | 50 | $17.0M | Research |
| Ambu-Star, INC | Transportation and Warehousing | $610,100 | $613,565 | 92 | $28.3M | Research |
| American Transmed INC | Administrative and Support and Waste Management | $586,000 | $592,007 | 107 | $20.2M | Research |
| Home Fashions International LLC | Manufacturing | $584,025 | $589,737 | 76 | $21.2M | Research |
| Burns Chevrolet INC | Retail Trade | $457,300 | $461,746 | 26 | $6.6M | Research |
| Flower Group USA LLC | Agriculture, Forestry, Fishing and Hunting | $432,200 | $434,568 | 51 | $5.2M | Research |
| Sossamon Construction Company, Inc. | Construction | $423,354 | $425,941 | 30 | $34.2M | Research |
| Bill Mason Enterprises LLC | Administrative and Support and Waste Management | $391,700 | $395,389 | 99 | $18.7M | Research |
| Hollywood's Productions, Inc. | Arts, Entertainment, and Recreation | $370,800 | $374,827 | 36 | $9.5M | Research |
| Roger Shiflett Ford, INC | Retail Trade | $330,700 | $332,739 | 43 | $10.8M | Research |
| Bwc Contracting INC | Construction | $297,400 | $300,068 | 29 | $6.7M | Research |
| Hollywoods Productions INC | Professional, Scientific, and Technical Services | $260,235 | $262,425 | 12 | <$5M | Research |
| Double R Utilities Inc. | Construction | $255,212 | $256,820 | 24 | $7.4M | Research |