| Yarbrough Termite & Pest Control, INC | Administrative and Support and Waste Management | $159,100 | $160,129 | 19 | <$5M |  AI Deep Dive |
| C.e.c Group LLC | Arts, Entertainment, and Recreation | $154,336 | $156,310 | 204 | $28.6M | AI Deep Dive |
| Thomas Hart Academy | Educational Services | $145,122 | $146,771 | 29 | N/A | AI Deep Dive |
| Hartsville Drug Company, INC | Retail Trade | $143,800 | $140,287 | 18 | <$5M | AI Deep Dive |
| Anderson Animal Hospital | Professional, Scientific, and Technical Services | $143,232 | $144,056 | 19 | <$5M | AI Deep Dive |
| Thomas Hart Academy | Educational Services | $141,797 | $143,349 | 31 | N/A | AI Deep Dive |
| Chafin, Johnson & Associates, LLC | Professional, Scientific, and Technical Services | $137,033 | $137,859 | 7 | <$5M | AI Deep Dive |
| Hartsville Ventures LLC | Accommodation and Food Services | $133,600 | $135,348 | 18 | $5.6M | AI Deep Dive |
| Black Creek Medical Consultants | Health Care and Social Assistance | $127,200 | $128,552 | 24 | $7.5M | AI Deep Dive |
| Goff Steakhouse LLC | Accommodation and Food Services | $123,502 | $124,298 | 37 | $6.6M | AI Deep Dive |
| Industrial Products & Services INC | Manufacturing | $123,065 | $124,407 | 9 | <$5M | AI Deep Dive |
| J&e Distributors INC | Wholesale Trade | $121,300 | $122,345 | 10 | <$5M | AI Deep Dive |
| Sk Hartsville LLC | Accommodation and Food Services | $115,800 | $116,726 | 49 | $8.7M | AI Deep Dive |
| Shoneys of Hartsville, INC | Accommodation and Food Services | $114,500 | $115,827 | 50 | $8.9M | AI Deep Dive |
| Johnson's Refrigeration Inc. | Construction | $114,400 | $115,306 | 15 | <$5M | AI Deep Dive |
| Precision Components & Services, LLC | Manufacturing | $113,997 | $114,681 | 5 | <$5M | AI Deep Dive |
| Johnsons Refrigeration INC | Construction | $109,100 | $110,045 | 13 | <$5M | AI Deep Dive |
| First Presbyterian Church | Other Services (except Public Administration) | $108,500 | $109,252 | 32 | N/A | AI Deep Dive |
| Precision Components & Services, LLC | Manufacturing | $108,400 | $119,279 | 5 | <$5M | AI Deep Dive |
| Darlington County Habitat for Humanity | Real Estate and Rental and Leasing | $106,582 | $107,274 | 31 | N/A | AI Deep Dive |
| Industrial Products & Services Inc. | Manufacturing | $106,300 | $107,683 | 9 | $8.9M | AI Deep Dive |
| Goff Seafood Inc. | Accommodation and Food Services | $105,131 | $105,790 | 16 | <$5M | AI Deep Dive |
| Palmetto Family Medicine and Senior Care, LLC | Health Care and Social Assistance | $104,167 | $105,206 | 16 | $5.0M | AI Deep Dive |
| Marshalls Frame & Collision, INC | Other Services (except Public Administration) | $103,935 | $104,986 | 16 | <$5M | AI Deep Dive |
| Darlington County Habitat for Humanity, LLC | Retail Trade | $102,800 | $103,876 | 20 | N/A | AI Deep Dive |