| The Greenery, Inc. | Retail Trade | $4,275,677 | $4,324,253 | 466 | $96.2M |  Research |
| Hilton Head Comedy Club INC | Arts, Entertainment, and Recreation | $3,407,400 | $34,464 | 3 | <$5M | Research |
| Memory Lane Portraits, Llc. | Arts, Entertainment, and Recreation | $2,777,300 | $28,089 | 2 | <$5M | Research |
| Ellis Construction Co., Inc. | Construction | $2,706,800 | $27,203 | 2 | <$5M | Research |
| Sdc Properties | Real Estate and Rental and Leasing | $2,166,900 | $1,642,278 | 245 | $36.8M | Research |
| Evs Brokerage Svcs | Real Estate and Rental and Leasing | $2,083,300 | $21,007 | 2 | <$5M | Research |
| Atlantic Resort Managers INC | Accommodation and Food Services | $2,000,000 | $2,017,556 | 208 | $65.0M | Research |
| Dewolff, Boberg and Associates, Inc. | Professional, Scientific, and Technical Services | $1,965,200 | $0 | 103 | $14.4M | Research |
| Atlantic Personnel, Inc. | Administrative and Support and Waste Management | $1,886,970 | $1,902,695 | 359 | $56.5M | Research |
| Charles Hebbel | Real Estate and Rental and Leasing | $1,750,000 | $8,795 | 1 | <$5M | Research |
| Atlantic Resort Managers, Inc. | Accommodation and Food Services | $1,615,222 | $1,633,483 | 208 | $65.0M | Research |
| Premier Marketing Ltd | Real Estate and Rental and Leasing | $1,482,100 | $10,468 | 1 | <$5M | Research |
| Haig Point Club and Community Association, Inc. | Other Services (except Public Administration) | $1,319,550 | $1,330,876 | 160 | $30.6M | Research |
| Serg Restaurant Group, LLC | Accommodation and Food Services | $1,270,800 | $1,279,149 | 114 | $20.2M | Research |
| Hudson Seafood Corporation | Accommodation and Food Services | $1,190,609 | $1,204,896 | 46 | $8.2M | Research |
| Healthplancrm LLC | Professional, Scientific, and Technical Services | $1,171,100 | $1,183,982 | 44 | $9.1M | Research |
| Moss Creek Owners' Association, Inc. | Other Services (except Public Administration) | $1,149,213 | $894,548 | 119 | $22.7M | Research |
| The Seabrook of Hilton Head, INC | Health Care and Social Assistance | $1,138,000 | $1,149,570 | 114 | $19.4M | Research |
| Community Services Associates Inc. | Other Services (except Public Administration) | $1,110,500 | $1,119,600 | 110 | N/A | Research |
| Wexford Plantation Home Owners Association, Inc. | Other Services (except Public Administration) | $1,080,522 | $1,089,376 | 98 | N/A | Research |
| Timperman INC | Real Estate and Rental and Leasing | $1,041,800 | $10,471 | 1 | <$5M | Research |
| Skull Creek Partners LLC | Accommodation and Food Services | $939,500 | $945,894 | 95 | $16.9M | Research |
| Hhps, INC | Educational Services | $924,700 | $932,277 | 84 | N/A | Research |
| H3 Hilton Head LLC | Accommodation and Food Services | $922,500 | $927,241 | 47 | $14.7M | Research |
| Resort Sales by Spinnaker Inc. | Administrative and Support and Waste Management | $890,500 | $651,106 | 99 | $18.7M | Research |