| Robert Savarese Dmd LLC | Health Care and Social Assistance | $118,107 | $119,010 | 12 | <$5M | Research |
| Ruby Lees South | Accommodation and Food Services | $114,530 | $0 | 23 | <$5M | Research |
| Hilton Head Hospitality LLC | Accommodation and Food Services | $112,238 | $113,376 | 16 | $5.0M | Research |
| Match Point Hilton Head LLC | Health Care and Social Assistance | $110,669 | $111,751 | 21 | <$5M | Research |
| Schuppert Properties LLC | Administrative and Support and Waste Management | $107,193 | $108,208 | 18 | <$5M | Research |
| Sea Island Wine and Gourmet Market LLC | Health Care and Social Assistance | $99,205 | $100,523 | 16 | <$5M | Research |
| Ejs Management LLC | Accommodation and Food Services | $96,772 | $97,672 | 5 | <$5M | Research |
| Mayes Internal Medicine, LLC | Health Care and Social Assistance | $94,776 | $95,721 | 7 | <$5M | Research |
| Hilton Head Dental Team LLC | Health Care and Social Assistance | $94,492 | $95,131 | 12 | <$5M | Research |
| Marlin Outdoor Advertising Ltd | Professional, Scientific, and Technical Services | $86,210 | $87,415 | 8 | <$5M | Research |
| Going Ward LLC | Professional, Scientific, and Technical Services | $86,200 | $87,270 | 7 | <$5M | Research |
| Surfs Up of Hilton Head INC | Retail Trade | $85,000 | $85,647 | 10 | <$5M | Research |
| Jamison Consultants, LLC | Professional, Scientific, and Technical Services | $82,835 | $84,075 | 22 | <$5M | Research |
| Ruby Lees South Llc-Sba Small 7a Term | Unknown | $81,807 | $0 | 23 | N/A | Research |
| Sffhhi Llc-Sba Small 7a Term | Unknown | $81,392 | $82,206 | 26 | N/A | Research |
| Sffpooler Slapfish-Sba Small 7a Term | Unknown | $81,092 | $81,903 | 26 | N/A | Research |
| Eurostone Machine Usa, Inc. | Manufacturing | $80,643 | $81,394 | 5 | <$5M | Research |
| Hilton Head Hospitality, LLC | Accommodation and Food Services | $80,170 | $81,020 | 16 | $5.0M | Research |
| D Hauser INC | Wholesale Trade | $78,165 | $78,805 | 4 | <$5M | Research |
| Hhi Rentals LLC | Real Estate and Rental and Leasing | $75,457 | $76,300 | 14 | $6.3M | Research |
| Impact Technology Group LLC | Other Services (except Public Administration) | $74,504 | $75,355 | 6 | <$5M | Research |
| The Urology Group | Health Care and Social Assistance | $70,000 | $0 | 7 | <$5M | Research |
| Arborcare Tree Experts Sc INC | Construction | $69,601 | $70,245 | 10 | <$5M | Research |
| Ejs Management LLC | Accommodation and Food Services | $69,122 | $70,059 | 5 | <$5M | Research |
| Bradshaw Group, Ltd. | Real Estate and Rental and Leasing | $68,465 | $64,646 | 3 | <$5M | Research |