| Hope Life and Rehab Center | Health Care and Social Assistance | $64,817 | $65,208 | 5 | <$5M | Research |
| Driftwood Enterprises, L.l.c. | Accommodation and Food Services | $62,500 | $62,885 | 20 | <$5M | Research |
| Hammer Hub LLC | Arts, Entertainment, and Recreation | $62,500 | $63,349 | 2 | <$5M | Research |
| Timothy Scharold MD LLC | Health Care and Social Assistance | $61,740 | $62,048 | 7 | <$5M | Research |
| Strauss Law Firm, LLC the | Professional, Scientific, and Technical Services | $61,458 | $62,204 | 3 | <$5M | Research |
| Coastal Pools and Fountains, Inc. | Construction | $59,097 | $59,828 | 7 | <$5M | Research |
| Nct Restaurants INC | Accommodation and Food Services | $58,411 | $59,219 | 60 | $10.7M | Research |
| Treasure Cove Adventure Golf Inc. | Arts, Entertainment, and Recreation | $56,900 | $57,257 | 13 | <$5M | Research |
| Treasure Cove Adventure Golf, Inc. | Arts, Entertainment, and Recreation | $56,400 | $56,868 | 23 | <$5M | Research |
| Monarch Roofing of Hilton Head, LLC | Construction | $56,132 | $56,650 | 8 | <$5M | Research |
| Kidz Planet Pediatric Dentistry Hhi PA | Health Care and Social Assistance | $55,700 | $47,498 | 6 | <$5M | Research |
| B2d2, LLC | Accommodation and Food Services | $53,400 | $53,938 | 14 | <$5M | Research |
| Land Speed Automotive LLC | Other Services (except Public Administration) | $52,500 | $53,013 | 6 | <$5M | Research |
| Association Renovation Consultants INC | Construction | $51,600 | $52,054 | 7 | <$5M | Research |
| The Hickey Group PA | Health Care and Social Assistance | $51,500 | $51,795 | 5 | <$5M | Research |
| Mi Tierra INC | Accommodation and Food Services | $50,925 | $51,429 | 8 | <$5M | Research |
| Thai Village Inc. | Accommodation and Food Services | $50,258 | $50,507 | 4 | <$5M | Research |
| Fleming Marine LLC | Other Services (except Public Administration) | $47,585 | $47,804 | 10 | <$5M | Research |
| Discover Specific Chiropractic INC | Health Care and Social Assistance | $45,624 | $45,998 | 8 | <$5M | Research |
| Mcnair Bldg Construction, INC | Construction | $45,000 | $45,483 | 4 | <$5M | Research |
| Dr Thomas P Lenns LLC | Health Care and Social Assistance | $44,856 | $45,258 | 2 | <$5M | Research |
| David E. Dorsner, M.d. | Health Care and Social Assistance | $43,020 | $43,399 | 8 | <$5M | Research |
| Marsh Side Owners Association INC | Real Estate and Rental and Leasing | $42,860 | $43,364 | 4 | N/A | Research |
| Innova Investments LLC | Professional, Scientific, and Technical Services | $42,340 | $42,562 | 7 | <$5M | Research |
| Renovators of Sc, Llc, the | Construction | $41,503 | $41,810 | 4 | <$5M | Research |