| Motley Rice, LLC | Professional, Scientific, and Technical Services | $7,034,400 | $7,114,514 | 379 | $92.1M |  Research |
| Bgi, LLC | Transportation and Warehousing | $6,324,228 | $6,217,420 | 411 | $32.0M | Research |
| Johnson & Johnson, Inc. | Finance and Insurance | $5,631,450 | $5,707,359 | 393 | $172.9M | Research |
| Verge Solutions, LLC | Information | $3,002,664 | $0 | 197 | $33.1M | Research |
| Seacoast Christian Community Church, Inc. | Other Services (except Public Administration) | $2,234,730 | $2,261,236 | 355 | $67.8M | Research |
| Seamon Whiteside and Associates INC | Administrative and Support and Waste Management | $2,138,200 | $2,096,403 | 109 | $20.6M | Research |
| Sticky Fingers Restaurants, LLC | Accommodation and Food Services | $2,000,000 | $1,402,638 | 138 | $24.5M | Research |
| Employers Health Network Holdings LLC | Finance and Insurance | $1,960,905 | $1,979,479 | 191 | $98.1M | Research |
| Spine Management LLC | Health Care and Social Assistance | $1,787,300 | $1,802,088 | 136 | $42.7M | Research |
| Lowcountry Grocers, LLC | Retail Trade | $1,732,800 | $1,748,324 | 488 | $121.9M | Research |
| Jear Logistics LLC | Professional, Scientific, and Technical Services | $1,584,900 | $1,594,255 | 118 | $16.5M | Research |
| Hubner Manufacturing Corporation | Manufacturing | $1,574,130 | $1,582,444 | 124 | $32.5M | Research |
| Quant Systems, INC | Information | $1,524,078 | $1,535,339 | 108 | $18.1M | Research |
| Sticky Fingers Restaurant LLC | Accommodation and Food Services | $1,488,300 | $1,246,815 | 311 | $55.2M | Research |
| Altron INC | Professional, Scientific, and Technical Services | $1,425,030 | $1,438,687 | 121 | $14.9M | Research |
| Sandpiper Rehab & Nursing - Delaware, LLC | Health Care and Social Assistance | $1,351,100 | $1,359,673 | 168 | $28.6M | Research |
| Ap Recovery INC | Professional, Scientific, and Technical Services | $1,350,000 | $1,359,062 | 68 | $7.0M | Research |
| L. Dean Weaver Company LLC | Construction | $1,350,000 | $1,359,263 | 102 | $31.6M | Research |
| Richardson Patrick Westbrook & Brickman LLC | Professional, Scientific, and Technical Services | $1,342,477 | $1,353,989 | 83 | $20.2M | Research |
| East Cooper Baptist Church | Other Services (except Public Administration) | $1,326,700 | $1,335,434 | 220 | N/A | Research |
| L Dean Weaver | Construction | $1,300,000 | $1,388,254 | 118 | $36.6M | Research |
| Peoplease LLC | Administrative and Support and Waste Management | $1,272,790 | $1,284,351 | 91 | $14.3M | Research |
| Millenia Medical Services, INC | Administrative and Support and Waste Management | $1,216,518 | $1,224,017 | 125 | $19.7M | Research |
| Dunhill Staffing Systems LLC | Administrative and Support and Waste Management | $1,208,333 | $1,217,106 | 58 | $9.1M | Research |
| Charleston Radiologists PA | Health Care and Social Assistance | $1,200,200 | $900,259 | 32 | $10.0M | Research |