| Darby Realty Company INC | Real Estate and Rental and Leasing | $658,254 | $667,001 | 64 | $11.7M | Research |
| Coastal Fertility Specialists LLC | Health Care and Social Assistance | $651,100 | $656,707 | 58 | $18.2M | Research |
| Christ Our King Stella Maris Catholic School | Educational Services | $649,731 | $658,106 | 111 | N/A | Research |
| Sundrops Group LLC | Educational Services | $641,700 | $647,440 | 75 | $9.0M | Research |
| Saltwater Cowboys LLC | Accommodation and Food Services | $635,612 | $642,162 | 70 | $12.4M | Research |
| Jdc Management LLC | Real Estate and Rental and Leasing | $630,600 | $635,265 | 62 | $9.3M | Research |
| Jdc Management LLC | Real Estate and Rental and Leasing | $628,400 | $632,584 | 53 | $8.0M | Research |
| East Cooper Montessori Charter School | Educational Services | $619,800 | $624,035 | 63 | N/A | Research |
| Myer's Heating and Air Conditioning, LLC | Construction | $615,000 | $620,415 | 61 | $20.8M | Research |
| Germain Dermatology Associates, PA | Health Care and Social Assistance | $608,360 | $613,700 | 50 | $15.7M | Research |
| Star Brands Ii, LLC | Accommodation and Food Services | $595,472 | $600,148 | 190 | $33.7M | Research |
| Mount Pleasant Manor,llc | Health Care and Social Assistance | $575,902 | $582,434 | 121 | $20.6M | Research |
| Starling Chevrolet Mp, LLC | Retail Trade | $560,500 | $565,844 | 39 | $9.8M | Research |
| Cmnd, LLC | Other Services (except Public Administration) | $530,873 | $471,321 | 165 | $31.5M | Research |
| Assignment Desk Works LLC | Information | $521,400 | $0 | 56 | $9.4M | Research |
| Dwg INC Consulting Engineers | Professional, Scientific, and Technical Services | $519,100 | $521,831 | 31 | <$5M | Research |
| Grace & Grit LLC | Accommodation and Food Services | $512,792 | $516,656 | 54 | $9.6M | Research |
| Mccay Kiddy LLC | Professional, Scientific, and Technical Services | $511,700 | $471,067 | 25 | $8.0M | Research |
| 1313 Corp. | Accommodation and Food Services | $508,991 | $514,081 | 67 | $11.9M | Research |
| Marketingprofs LLC | Educational Services | $497,100 | $500,870 | 24 | <$5M | Research |
| Red Drum, Mp, LLC | Accommodation and Food Services | $490,459 | $494,745 | 57 | $10.1M | Research |
| Charleston Imaging Products INC | Professional, Scientific, and Technical Services | $476,415 | $354,207 | 36 | $7.4M | Research |
| Mccay Kiddy LLC | Professional, Scientific, and Technical Services | $467,185 | $469,547 | 32 | $10.2M | Research |
| Baker Motor Company of Mt. Pleasant, LLC | Retail Trade | $464,021 | $469,151 | 31 | $7.8M | Research |
| Hunter Quinn Homes, LLC | Construction | $462,363 | $464,858 | 31 | $9.4M | Research |