| Chapel Creek Associates, LLC | Arts, Entertainment, and Recreation | $70,737 | $71,462 | 13 | <$5M | AI Deep Dive |
| Willshire Farms, Inc. | Agriculture, Forestry, Fishing and Hunting | $68,648 | $69,483 | 11 | <$5M | AI Deep Dive |
| Om Shree Sai Nath, LLC | Accommodation and Food Services | $65,400 | $65,852 | 13 | <$5M | AI Deep Dive |
| W. Scott Palmer Law Firm, P.a. | Professional, Scientific, and Technical Services | $61,289 | $61,825 | 5 | <$5M | AI Deep Dive |
| S C Oil Co., Inc. | Retail Trade | $59,820 | $60,579 | 16 | <$5M | AI Deep Dive |
| S.c. Oil Co Inc. | Retail Trade | $59,163 | $59,778 | 14 | <$5M | AI Deep Dive |
| Santee Adult Daycare LLC | Health Care and Social Assistance | $59,058 | $59,320 | 18 | <$5M | AI Deep Dive |
| Dantzler Farms | Agriculture, Forestry, Fishing and Hunting | $57,687 | $58,339 | 8 | <$5M | AI Deep Dive |
| G.l. Smith Inc. | Retail Trade | $57,133 | $57,477 | 14 | <$5M | AI Deep Dive |
| G.l. Smith, Inc. | Retail Trade | $57,132 | $57,618 | 14 | <$5M | AI Deep Dive |
| Santee Modular Homes Inc. | Construction | $56,900 | $57,528 | 7 | <$5M | AI Deep Dive |
| Golf Santee, Inc. | Arts, Entertainment, and Recreation | $48,975 | $49,312 | 4 | <$5M | AI Deep Dive |
| Golf Santee Inc. | Arts, Entertainment, and Recreation | $46,773 | $46,981 | 6 | <$5M | AI Deep Dive |
| Russell N Hewitt DBA Rusty Hewitt Insurance DBA State Farm | Finance and Insurance | $46,638 | $47,192 | 4 | <$5M | AI Deep Dive |
| Krishna2016 LLC | Accommodation and Food Services | $45,269 | $45,492 | 10 | <$5M | AI Deep Dive |
| Ted C. Shuler & Sons | Agriculture, Forestry, Fishing and Hunting | $41,100 | $41,512 | 4 | <$5M | AI Deep Dive |
| Santee Insurance Center, Inc. | Finance and Insurance | $40,665 | $40,991 | 10 | $5.1M | AI Deep Dive |
| Sb Construction Inc. | Construction | $40,500 | $41,018 | 5 | $5.7M | AI Deep Dive |
| Santee Adult Day Care, LLC | Health Care and Social Assistance | $39,590 | $39,940 | 18 | <$5M | AI Deep Dive |
| Santee Quick Lube, Inc. | Other Services (except Public Administration) | $39,065 | $39,349 | 8 | <$5M | AI Deep Dive |
| Sb Construction Inc. | Construction | $39,000 | $39,374 | 5 | <$5M | AI Deep Dive |
| Lane Kelley Properties, LLC | Real Estate and Rental and Leasing | $38,385 | $38,711 | 3 | <$5M | AI Deep Dive |
| Krishna2016 LLC | Accommodation and Food Services | $36,207 | $36,547 | 10 | <$5M | AI Deep Dive |
| Santee Cooper Country Club, INC | Arts, Entertainment, and Recreation | $36,080 | $36,287 | 10 | <$5M | AI Deep Dive |
| Santee Auto Parts, Inc. | Retail Trade | $35,908 | $36,161 | 7 | <$5M | AI Deep Dive |