| P.m.i.2, Inc. | Manufacturing | $272,600 | $275,229 | 22 | $5.8M |  AI Deep Dive |
| Arsenal Taco Clemson LLC | Accommodation and Food Services | $271,628 | $274,597 | 48 | $8.5M | AI Deep Dive |
| Bountyland Petroleum Inc. | Retail Trade | $265,000 | $266,822 | 20 | $6.7M | AI Deep Dive |
| Upstate Medical Associates, P.a. | Health Care and Social Assistance | $242,485 | $244,546 | 42 | $7.5M | AI Deep Dive |
| Performance Powersports LLC | Retail Trade | $236,000 | $237,409 | 25 | $6.5M | AI Deep Dive |
| Thrift Brothers, Inc. | Construction | $232,920 | $235,832 | 22 | $6.7M | AI Deep Dive |
| Kroeger Marine Construction INC | Construction | $231,800 | $234,493 | 1 | <$5M | AI Deep Dive |
| Onetone Telecom INC | Information | $217,777 | $220,324 | 19 | <$5M | AI Deep Dive |
| Lowery Oil Company INC | Retail Trade | $211,712 | $214,229 | 36 | $12.0M | AI Deep Dive |
| Foothills Area Ymca, the | Health Care and Social Assistance | $210,000 | $116,928 | 100 | N/A | AI Deep Dive |
| Lowry Oil Company INC | Retail Trade | $202,247 | $204,034 | 38 | $12.7M | AI Deep Dive |
| Anesthesiology Consultants of the Upstat | Health Care and Social Assistance | $197,537 | $190,242 | 6 | <$5M | AI Deep Dive |
| Dienners Kitchen INC | Accommodation and Food Services | $196,780 | $199,524 | 42 | $7.5M | AI Deep Dive |
| Seneca Animal Hospital PA | Professional, Scientific, and Technical Services | $189,648 | $191,232 | 38 | $5.3M | AI Deep Dive |
| Anesthesiology Consultants of the Upstat | Health Care and Social Assistance | $188,344 | $190,300 | 6 | <$5M | AI Deep Dive |
| Oconee Pediatrics | Health Care and Social Assistance | $186,392 | $188,033 | 17 | <$5M | AI Deep Dive |
| Copper River Grill, LLC | Accommodation and Food Services | $186,242 | $189,036 | 41 | $7.3M | AI Deep Dive |
| Joe's New York Pizza INC | Accommodation and Food Services | $182,000 | $184,083 | 22 | <$5M | AI Deep Dive |
| Jet Commercial LLC | Construction | $181,920 | $183,664 | 19 | $6.0M | AI Deep Dive |
| Oconee Pediatrics, P.a. | Health Care and Social Assistance | $175,825 | $177,300 | 14 | <$5M | AI Deep Dive |
| Copper River Grill LLC | Accommodation and Food Services | $171,158 | $173,355 | 26 | <$5M | AI Deep Dive |
| Foxnest Veterinary Hospital LLC | Professional, Scientific, and Technical Services | $171,150 | $172,443 | 25 | <$5M | AI Deep Dive |
| Carolina Lung and Sleep Center | Health Care and Social Assistance | $167,960 | $169,104 | 15 | <$5M | AI Deep Dive |
| Foxnest Veterinary Hospital LLC | Professional, Scientific, and Technical Services | $167,700 | $169,834 | 27 | <$5M | AI Deep Dive |
| Clemson Family Dentistry LLC | Health Care and Social Assistance | $163,361 | $164,400 | 12 | <$5M | AI Deep Dive |