| Best Services of Oconee Inc. | Construction | $153,800 | $154,663 | 16 | $5.1M | AI Deep Dive |
| Oconee Christian Academy | Other Services (except Public Administration) | $150,433 | $152,003 | 34 | N/A | AI Deep Dive |
| Dienners Kitchen INC | Accommodation and Food Services | $149,545 | $151,796 | 10 | <$5M | AI Deep Dive |
| Blue Ridge Eye Center PA | Health Care and Social Assistance | $147,400 | $148,309 | 12 | <$5M | AI Deep Dive |
| Teriad Group International | Finance and Insurance | $146,425 | $0 | 8 | <$5M | AI Deep Dive |
| Zone 7 INC | Retail Trade | $145,622 | $146,989 | 21 | <$5M | AI Deep Dive |
| Twin Lakes Auto Body Corp. | Other Services (except Public Administration) | $145,270 | $146,492 | 14 | <$5M | AI Deep Dive |
| Fastfetch Corporation | Professional, Scientific, and Technical Services | $140,500 | $141,839 | 8 | <$5M | AI Deep Dive |
| Instacom, Inc. | Construction | $139,720 | $140,627 | 9 | <$5M | AI Deep Dive |
| Clemson Marina and Campground LLC | Arts, Entertainment, and Recreation | $138,523 | $140,031 | 37 | $5.2M | AI Deep Dive |
| Wendy's Pub & Grub LLC | Accommodation and Food Services | $137,704 | $0 | 72 | $12.8M | AI Deep Dive |
| Carolina Lung & Sleep Center LLC | Health Care and Social Assistance | $135,652 | $136,651 | 14 | <$5M | AI Deep Dive |
| Blue Ridge Eye Center, PA | Health Care and Social Assistance | $133,100 | $134,380 | 12 | <$5M | AI Deep Dive |
| Clemson Cleaning Services INC | Administrative and Support and Waste Management | $132,716 | $133,645 | 56 | $12.1M | AI Deep Dive |
| Clemson Cleaning Services, INC | Administrative and Support and Waste Management | $130,555 | $131,755 | 31 | $6.7M | AI Deep Dive |
| Joe's New York Pizza INC | Accommodation and Food Services | $130,000 | $130,955 | 13 | <$5M | AI Deep Dive |
| Fastfetch Corporation | Professional, Scientific, and Technical Services | $127,337 | $128,002 | 8 | <$5M | AI Deep Dive |
| Southern Senior Care, Inc. | Health Care and Social Assistance | $125,035 | $126,921 | 57 | $9.8M | AI Deep Dive |
| Willow Lake Buildings LLC | Manufacturing | $124,479 | $125,488 | 12 | $11.9M | AI Deep Dive |
| Technology Solutions of Sc, Inc. | Professional, Scientific, and Technical Services | $124,238 | $125,153 | 12 | <$5M | AI Deep Dive |
| Keowee Family Dentistry, PA | Health Care and Social Assistance | $122,455 | $103,525 | 11 | <$5M | AI Deep Dive |
| Wendy's Pub & Grub, LLC | Accommodation and Food Services | $122,017 | $123,176 | 24 | <$5M | AI Deep Dive |
| Cross Creek Plantation | Arts, Entertainment, and Recreation | $117,169 | $117,820 | 24 | <$5M | AI Deep Dive |
| Lei Partners LLC | Transportation and Warehousing | $116,750 | $117,380 | 9 | <$5M | AI Deep Dive |
| Bari Company Inc. | Accommodation and Food Services | $115,864 | $116,948 | 18 | <$5M | AI Deep Dive |