| Lowcountry Women's Specialists, P.a. | Health Care and Social Assistance | $596,300 | $600,159 | 61 | $19.1M |  AI Deep Dive |
| A. Frederick Solomon Dmd PA | Health Care and Social Assistance | $574,200 | $577,741 | 73 | $16.9M | AI Deep Dive |
| Z Marine North America LLC | Administrative and Support and Waste Management | $535,900 | $540,753 | 39 | $7.4M | AI Deep Dive |
| Faith Assembly of God | Other Services (except Public Administration) | $485,767 | $489,410 | 106 | N/A | AI Deep Dive |
| Norton & Richardson Paint & Body Shop, Inc. | Other Services (except Public Administration) | $483,600 | $486,220 | 29 | $5.7M | AI Deep Dive |
| Holy Ship LLC | Transportation and Warehousing | $465,500 | $471,655 | 69 | $10.4M | AI Deep Dive |
| Chris Thompson Services, LLC | Transportation and Warehousing | $464,921 | $470,384 | 32 | <$5M | AI Deep Dive |
| Cahoc 7, LLC | Accommodation and Food Services | $455,835 | $461,140 | 96 | $17.0M | AI Deep Dive |
| Dbw Fiber Corporation | Transportation and Warehousing | $453,976 | $46,009 | 2 | <$5M | AI Deep Dive |
| Charleston Symphony Orchestra | Arts, Entertainment, and Recreation | $447,988 | $451,298 | 18 | N/A | AI Deep Dive |
| Mjd Enterprises, Inc. | Accommodation and Food Services | $445,805 | $450,065 | 51 | $9.1M | AI Deep Dive |
| Z Nautic Sas | Manufacturing | $443,897 | $448,743 | 37 | $9.7M | AI Deep Dive |
| Upstairs at the Ice House Inc. | Accommodation and Food Services | $442,400 | $445,539 | 46 | $8.2M | AI Deep Dive |
| Summerville Family Young Men's Christian Association | Other Services (except Public Administration) | $421,800 | $427,799 | 228 | N/A | AI Deep Dive |
| Summerville Family Young Men's Christian Association | Other Services (except Public Administration) | $421,768 | $427,766 | 192 | N/A | AI Deep Dive |
| Hunter Specialties INC | Construction | $412,500 | $415,559 | 40 | $13.2M | AI Deep Dive |
| B&e Electrical, Inc. | Construction | $412,400 | $415,504 | 29 | $9.5M | AI Deep Dive |
| Bracewell Construction Company, LLC | Transportation and Warehousing | $408,385 | $374,470 | 32 | <$5M | AI Deep Dive |
| Grand Forest INC | Administrative and Support and Waste Management | $408,100 | $412,668 | 45 | $8.5M | AI Deep Dive |
| Sweetgrass Plastic Surgery | Health Care and Social Assistance | $389,404 | $392,199 | 37 | $7.3M | AI Deep Dive |
| Innovative Waste Management Inc. | Wholesale Trade | $386,500 | $389,518 | 22 | $6.7M | AI Deep Dive |
| B&e Electrical INC | Construction | $384,487 | $385,608 | 23 | $7.6M | AI Deep Dive |
| American Payroll Corporation | Professional, Scientific, and Technical Services | $383,104 | $385,381 | 42 | $13.4M | AI Deep Dive |
| Charleston Endoscopy Center, LLC | Health Care and Social Assistance | $381,015 | $384,613 | 54 | $16.9M | AI Deep Dive |
| H & J Contracting of Sc, LLC | Construction | $380,200 | $384,262 | 29 | $9.9M | AI Deep Dive |