| Gulf Coast Ford, Ltd | Retail Trade | $2,717,200 | $2,749,136 | 330 | $83.2M |  Research |
| Country Village Care, Inc. | Health Care and Social Assistance | $819,800 | $824,741 | 160 | $27.2M | Research |
| Serenity Light Recovery, LLC | Health Care and Social Assistance | $695,807 | $647,466 | 44 | $7.5M | Research |
| Davis Air Conditioning & Heating INC | Construction | $674,800 | $678,590 | 64 | $20.2M | Research |
| Serenity Light Recovery LLC | Health Care and Social Assistance | $600,312 | $609,333 | 44 | $7.5M | Research |
| Samson Fabricators, LLC | Manufacturing | $489,208 | $492,007 | 94 | $24.6M | Research |
| Samson Fabricators, LLC | Manufacturing | $489,208 | $493,067 | 30 | $7.9M | Research |
| Lc Angleton LLC | Accommodation and Food Services | $445,800 | $450,890 | 84 | $14.9M | Research |
| Overnite Software Inc. | Professional, Scientific, and Technical Services | $410,700 | $413,671 | 35 | $7.2M | Research |
| Overnite Software, Inc. | Educational Services | $397,300 | $400,272 | 39 | $5.2M | Research |
| Collins Instrument Co., Inc. | Manufacturing | $396,700 | $399,178 | 21 | $5.1M | Research |
| Ojl Construction, LLC | Construction | $365,500 | $369,916 | 40 | $45.6M | Research |
| Felder Water Well & Pump Service, LLC | Construction | $361,600 | $363,617 | 18 | $6.1M | Research |
| Brazoria County Association for Citizens With Handicaps | Health Care and Social Assistance | $343,900 | $346,359 | 34 | N/A | Research |
| Angleton Area Emergency Medical Corps INC | Health Care and Social Assistance | $332,600 | $335,289 | 25 | N/A | Research |
| Chastang Enterprises - Angleton, LLC | Retail Trade | $307,600 | $272,631 | 27 | $6.8M | Research |
| Scott M. Brown, P.c. | Professional, Scientific, and Technical Services | $307,300 | $309,010 | 19 | <$5M | Research |
| Scott M Brown P.c. | Professional, Scientific, and Technical Services | $307,000 | $308,305 | 19 | <$5M | Research |
| Manjit S Randhawa D.o. P.a. | Health Care and Social Assistance | $304,048 | $305,433 | 18 | $5.6M | Research |
| Manjit S Randhawa D.o., P.a. | Health Care and Social Assistance | $304,000 | $305,924 | 18 | $5.6M | Research |
| R R Ramsower INC | Manufacturing | $294,255 | $245,434 | 29 | $7.1M | Research |
| R R Ramsower INC | Manufacturing | $294,250 | $295,314 | 31 | $7.6M | Research |
| Bobby Ford Tractor & Equipment, LLC | Wholesale Trade | $284,000 | $285,743 | 22 | $6.7M | Research |
| Boys and Girls Club of Brazoria County | Health Care and Social Assistance | $283,533 | $285,517 | 68 | N/A | Research |
| Angleton Christian School Corporation | Educational Services | $276,015 | $277,579 | 49 | $5.9M | Research |