| Angleton Christian School Corporation | Educational Services | $273,400 | $275,800 | 46 | $5.5M |  Research |
| Baker & Lawson, Inc. | Professional, Scientific, and Technical Services | $252,600 | $253,936 | 13 | <$5M | Research |
| Goe Kawasaki INC | Retail Trade | $248,200 | $249,825 | 22 | $5.7M | Research |
| Salim F Dabaghi MD PA | Health Care and Social Assistance | $240,722 | $244,053 | 19 | $6.0M | Research |
| Iso Therapeutics Group LLC | Manufacturing | $228,800 | $230,177 | 14 | <$5M | Research |
| Tex-Con Construction Services LLC | Construction | $227,500 | $228,366 | 31 | $35.3M | Research |
| Kwp Management, LLC | Health Care and Social Assistance | $226,700 | $227,953 | 15 | <$5M | Research |
| Aspen Rentals, Inc. | Real Estate and Rental and Leasing | $219,400 | $220,686 | 13 | $5.9M | Research |
| Scarlet Lounge Incorporated | Accommodation and Food Services | $218,995 | $58,510 | 13 | <$5M | Research |
| Sar Solutions Inc. | Retail Trade | $217,500 | $219,735 | 37 | $7.6M | Research |
| Oscar Lerma | Construction | $212,127 | $215,312 | 20 | $22.8M | Research |
| Iso Therapeutics Group LLC | Professional, Scientific, and Technical Services | $210,200 | $211,427 | 15 | <$5M | Research |
| Angleton Foursquare Church | Other Services (except Public Administration) | $208,000 | $209,408 | 28 | $5.3M | Research |
| Android Construction Services, LLC | Construction | $205,800 | $206,612 | 22 | $25.1M | Research |
| Aspen Rentals Inc. | Real Estate and Rental and Leasing | $203,140 | $203,936 | 26 | $11.7M | Research |
| Jaco Roofing & Construction INC | Construction | $198,900 | $200,927 | 14 | <$5M | Research |
| Coastal Machine and Mechanical LLC | Manufacturing | $197,200 | $199,123 | 20 | <$5M | Research |
| Coastal Machine and Mechanical LLC | Manufacturing | $197,200 | $198,561 | 20 | <$5M | Research |
| Jaco Roofing & Construction INC | Construction | $195,400 | $196,926 | 11 | $12.5M | Research |
| Welty Services LLC | Retail Trade | $193,078 | $193,785 | 16 | <$5M | Research |
| Angleton Er Pllc | Health Care and Social Assistance | $190,900 | $192,645 | 43 | $7.7M | Research |
| Jarrod Smith | Professional, Scientific, and Technical Services | $189,000 | $191,289 | 18 | <$5M | Research |
| Noble Building & Development LLC | Construction | $188,300 | $189,017 | 12 | $13.7M | Research |
| Noble Building & Development, LLC | Construction | $178,700 | $179,787 | 14 | $16.0M | Research |
| Texcon Construction Services | Construction | $177,500 | $178,379 | 17 | $5.3M | Research |