| Elena Y Francisco, Inc. | Accommodation and Food Services | $1,927,664 | $1,947,786 | 293 | $52.0M | AI Deep Dive |
| Carecetera Home Care, Inc. | Health Care and Social Assistance | $783,000 | $794,713 | 371 | $63.5M | AI Deep Dive |
| De La Paz Cleaning & Rental Service LLC | Administrative and Support and Waste Management | $568,400 | $574,972 | 133 | $28.8M | AI Deep Dive |
| Plr Furniture, INC | Retail Trade | $535,203 | $539,220 | 57 | $10.3M | AI Deep Dive |
| Frio Distributing LLC | Wholesale Trade | $494,710 | $498,207 | 62 | $16.0M | AI Deep Dive |
| Ram Country Chrysler-Dodge Del Rio | Retail Trade | $435,060 | $438,202 | 42 | $10.6M | AI Deep Dive |
| Brown Automotive Center, Inc. | Wholesale Trade | $403,975 | $408,138 | 48 | $14.7M | AI Deep Dive |
| Val Verde Home Nurses, Inc. | Health Care and Social Assistance | $397,402 | $400,048 | 317 | $54.3M | AI Deep Dive |
| Del Rio Comfort Tech Ltd | Construction | $370,048 | $373,231 | 28 | $8.9M | AI Deep Dive |
| Emja LLC | Accommodation and Food Services | $363,957 | $366,340 | 61 | $10.8M | AI Deep Dive |
| Ventura Promotional Products, Inc. | Manufacturing | $350,722 | $352,702 | 42 | $41.7M | AI Deep Dive |
| Ventura Promotional Products INC | Manufacturing | $350,722 | $352,769 | 44 | $43.6M | AI Deep Dive |
| Julio's Seasoning & Corn Chips, Inc. | Accommodation and Food Services | $345,531 | $347,888 | 60 | $10.7M | AI Deep Dive |
| Khoury Automotive of Del Rio, INC | Other Services (except Public Administration) | $342,429 | $344,902 | 41 | $8.0M | AI Deep Dive |
| Frontera Construction, LLC | Construction | $321,000 | $325,177 | 32 | $36.5M | AI Deep Dive |
| Del Rio & Caraway, P.c. | Public Administration | $300,000 | $304,158 | 23 | N/A | AI Deep Dive |
| Brown Nissan of Del Rio, Inc. | Wholesale Trade | $297,262 | $300,375 | 32 | $9.8M | AI Deep Dive |
| Cecil Atkission Ford Lincoln, LLC | Other Services (except Public Administration) | $285,600 | $287,439 | 32 | $6.3M | AI Deep Dive |
| Frontera Construction LLC | Construction | $262,700 | $265,601 | 28 | $31.9M | AI Deep Dive |
| Isenhour Management, Inc. | Accommodation and Food Services | $260,785 | $221,650 | 35 | $6.2M | AI Deep Dive |
| Delrio Ventrue LP | Accommodation and Food Services | $228,165 | $230,009 | 65 | $11.5M | AI Deep Dive |
| Jay Mack's Enterprises, INC | Construction | $225,800 | $229,673 | 26 | $8.6M | AI Deep Dive |
| Jay Macks Enterprises INC | Construction | $225,800 | $228,924 | 26 | $8.6M | AI Deep Dive |
| Max & Mac, LLC | Accommodation and Food Services | $222,500 | $224,969 | 46 | $14.4M | AI Deep Dive |
| Severino Sanchez Jr INC | Transportation and Warehousing | $217,153 | $218,480 | 17 | <$5M | AI Deep Dive |