| Cesar Costa Luna MD PA and Associates | Health Care and Social Assistance | $187,400 | $140,255 | 23 | $7.2M | AI Deep Dive |
| 2105 W. Lincoln, Ltd | Accommodation and Food Services | $185,500 | $187,248 | 59 | $10.5M | AI Deep Dive |
| Torniquete, LLC | Accommodation and Food Services | $185,447 | $186,541 | 85 | $15.1M | AI Deep Dive |
| Hino Gas Sales INC | Retail Trade | $181,520 | $183,340 | 35 | $8.4M | AI Deep Dive |
| Valley Children's Clinic | Health Care and Social Assistance | $181,415 | $128,376 | 18 | $5.6M | AI Deep Dive |
| Athc Provider Services, Inc. | Health Care and Social Assistance | $181,390 | $183,400 | 75 | $12.8M | AI Deep Dive |
| Macpherson Ltd | Retail Trade | $181,200 | $182,883 | 22 | <$5M | AI Deep Dive |
| Bryant & Stingley INC | Professional, Scientific, and Technical Services | $180,467 | $181,268 | 17 | <$5M | AI Deep Dive |
| Harlingen Anesthesia Associates | Health Care and Social Assistance | $179,320 | $182,299 | 13 | <$5M | AI Deep Dive |
| Stephanie H Garcia M.d. P.a. | Health Care and Social Assistance | $175,000 | $176,980 | 18 | $5.6M | AI Deep Dive |
| Harlingen Hotels Inc. | Accommodation and Food Services | $174,016 | $176,047 | 30 | $9.4M | AI Deep Dive |
| South Texas Immigration Council | Public Administration | $173,749 | $175,009 | 18 | N/A | AI Deep Dive |
| Delta Temp Services LLC | Construction | $172,300 | $173,310 | 27 | $8.5M | AI Deep Dive |
| Delta Temp Services LLC | Administrative and Support and Waste Management | $172,300 | $173,858 | 23 | <$5M | AI Deep Dive |
| Hess & Turner INC | Retail Trade | $171,165 | $172,891 | 34 | $7.0M | AI Deep Dive |
| Marg-Tiff , Inc. | Construction | $170,600 | $171,577 | 21 | $6.5M | AI Deep Dive |
| Marg-Tiff , Inc. | Construction | $170,600 | $171,778 | 21 | $6.5M | AI Deep Dive |
| Sort-Rite International Inc. | Manufacturing | $167,900 | $168,659 | 20 | $5.6M | AI Deep Dive |
| Sort-Rite International, Inc. | Manufacturing | $167,900 | $168,875 | 23 | $6.4M | AI Deep Dive |
| Harlingen Gin Company | Agriculture, Forestry, Fishing and Hunting | $167,300 | $169,097 | 9 | <$5M | AI Deep Dive |
| Harlingen Gin Company | Agriculture, Forestry, Fishing and Hunting | $167,000 | $168,089 | 4 | <$5M | AI Deep Dive |
| Rio Grande Medicine INC | Health Care and Social Assistance | $166,600 | $168,446 | 21 | $6.6M | AI Deep Dive |
| Hino Gas Sales Incorporated | Utilities | $166,560 | $163,899 | 32 | N/A | AI Deep Dive |
| Diana Lozano MD PA | Health Care and Social Assistance | $166,275 | $168,991 | 17 | $5.3M | AI Deep Dive |
| Muniz Rio Grande Pharmacy, LLC | Retail Trade | $163,283 | $164,388 | 22 | <$5M | AI Deep Dive |