| Regence Health Network INC | Health Care and Social Assistance | $1,790,700 | $1,806,304 | 163 | N/A |  Research |
| United Ag LLC | Agriculture, Forestry, Fishing and Hunting | $1,122,400 | $1,132,190 | 125 | $20.5M | Research |
| Radar Supports, LLC | Administrative and Support and Waste Management | $1,106,640 | $1,119,090 | 49 | $7.7M | Research |
| Radar Supports LLC | Administrative and Support and Waste Management | $1,104,168 | $1,110,608 | 49 | $7.7M | Research |
| Gebo Distributing Co, Inc. | Retail Trade | $1,100,000 | $1,110,247 | 193 | $39.8M | Research |
| Fred Garrison Oil Company | Wholesale Trade | $812,203 | $819,479 | 45 | $11.6M | Research |
| Fred Garrison Oil Company | Retail Trade | $812,200 | $817,229 | 46 | $11.0M | Research |
| County Services INC | Manufacturing | $744,100 | $748,379 | 68 | $24.0M | Research |
| West Texas Family Medicine | Health Care and Social Assistance | $709,615 | $717,489 | 70 | $22.0M | Research |
| Legacy Farms, LP | Agriculture, Forestry, Fishing and Hunting | $693,900 | $699,663 | 89 | $14.6M | Research |
| Plainview Bioenergy, LLC | Manufacturing | $688,812 | $697,344 | 63 | $62.5M | Research |
| Plainview Bioenergy LLC | Manufacturing | $688,800 | $552,628 | 63 | $62.5M | Research |
| West Texas Family Medicine, Pllc | Health Care and Social Assistance | $591,000 | $596,100 | 69 | $21.7M | Research |
| Prairie Rehab & Nursing Gs LLC | Health Care and Social Assistance | $528,500 | $537,323 | 78 | $13.3M | Research |
| Radar Foundations, Inc. | Health Care and Social Assistance | $523,000 | $527,998 | 33 | N/A | Research |
| J&s Rides Inc. | Manufacturing | $515,673 | $522,228 | 41 | $10.7M | Research |
| J & S Rides, INC | Manufacturing | $515,600 | $521,024 | 41 | $10.7M | Research |
| James Brothers Implement Co., | Other Services (except Public Administration) | $482,500 | $374,093 | 25 | $5.4M | Research |
| Vista Grande Dairy Ltd Co LLC | Agriculture, Forestry, Fishing and Hunting | $469,000 | $474,589 | 50 | $8.2M | Research |
| Vista Grande Dairy | Agriculture, Forestry, Fishing and Hunting | $448,200 | $452,227 | 49 | $8.0M | Research |
| Heifer Ranch at Arroyo Seco Ltd | Agriculture, Forestry, Fishing and Hunting | $420,000 | $423,038 | 36 | $5.9M | Research |
| Allegiance Behavioral Health Center of Plainview | Health Care and Social Assistance | $389,617 | $396,847 | 70 | $11.9M | Research |
| Rotom INC | Manufacturing | $349,200 | $352,415 | 27 | $6.6M | Research |
| Hope Hastey | Construction | $326,770 | $328,222 | 24 | $7.3M | Research |
| Radar Supports Construction | Construction | $326,770 | $330,083 | 24 | $7.3M | Research |