| Lewis Kaufman Reid Stukey Gattis & Co PC | Professional, Scientific, and Technical Services | $314,600 | $317,375 | 22 | $7.0M | Research |
| Fresh Contracting LLC | Wholesale Trade | $310,357 | $272,003 | 25 | $6.4M | Research |
| Area Community Hospice, INC | Health Care and Social Assistance | $292,500 | $294,944 | 30 | $5.1M | Research |
| Bill Wells Chevrolet LP | Retail Trade | $286,600 | $289,081 | 26 | $6.6M | Research |
| Coffey Forage Seeds, Inc. | Agriculture, Forestry, Fishing and Hunting | $277,100 | $278,732 | 21 | <$5M | Research |
| Lewis, Kaufman, Reid, Stukey, Gattis & Co., PC | Professional, Scientific, and Technical Services | $256,700 | $316,410 | 23 | $7.3M | Research |
| M Hastey Construction Co INC | Mining, Quarrying, and Oil and Gas Extraction | $249,428 | $250,623 | 15 | <$5M | Research |
| M. Hasty Construction Co. INC | Construction | $249,400 | $251,306 | 18 | $6.1M | Research |
| Quarterway Cotton Growers LLC | Agriculture, Forestry, Fishing and Hunting | $237,629 | $240,689 | 13 | <$5M | Research |
| Fox Dairy, Ltd | Agriculture, Forestry, Fishing and Hunting | $234,700 | $236,065 | 31 | $5.1M | Research |
| Empresa Primos INC | Accommodation and Food Services | $230,956 | $233,426 | 26 | <$5M | Research |
| Descanso Dairy LLC | Agriculture, Forestry, Fishing and Hunting | $226,200 | $228,096 | 23 | <$5M | Research |
| Bradley Holding LLP | Retail Trade | $222,700 | $0 | 30 | $7.6M | Research |
| High Plains Radio Network LLC | Information | $221,100 | $222,728 | 34 | $5.7M | Research |
| Plainview Hospice, LP | Health Care and Social Assistance | $216,300 | $218,601 | 21 | <$5M | Research |
| Rodrigo Fonseca | Agriculture, Forestry, Fishing and Hunting | $208,332 | $25,360 | 2 | <$5M | Research |
| 1st Alarm, INC | Construction | $193,300 | $194,879 | 22 | $7.2M | Research |
| Western Ag Sales Co INC | Manufacturing | $186,978 | $189,083 | 24 | $23.8M | Research |
| South Plains Precision Ag., Inc. | Agriculture, Forestry, Fishing and Hunting | $184,202 | $185,277 | 12 | <$5M | Research |
| South Plains Precision Ag Inc. | Wholesale Trade | $184,202 | $184,918 | 12 | <$5M | Research |
| Texas Agri Machine and Industrial Mfg | Manufacturing | $181,613 | $182,523 | 23 | $5.6M | Research |
| Texas Agri Machine and Industrial Mfg | Other Services (except Public Administration) | $181,600 | $182,923 | 36 | $7.1M | Research |
| Tortillas Ricas LP | Manufacturing | $179,400 | $181,199 | 34 | $12.0M | Research |
| High Plains Radio Network, LLC | Information | $179,300 | $222,820 | 34 | $5.7M | Research |
| Quarterway Cotton Growers, LLC | Agriculture, Forestry, Fishing and Hunting | $176,600 | $177,679 | 13 | <$5M | Research |