| Building Specialists, Inc. | Construction | $237,497 | $239,905 | 24 | $27.3M | AI Deep Dive |
| Arellano Valley View INC | Accommodation and Food Services | $237,440 | $238,733 | 28 | <$5M | AI Deep Dive |
| Roanoke Cooperative Association, Ltd. | Retail Trade | $236,700 | $238,580 | 46 | $5.1M | AI Deep Dive |
| Lumsden Associates P.c. | Real Estate and Rental and Leasing | $236,090 | $237,041 | 20 | <$5M | AI Deep Dive |
| Justin Roanoke Hotel, LLC | Accommodation and Food Services | $235,000 | $237,150 | 47 | $14.7M | AI Deep Dive |
| Lynch Dickey & Singleton Dentists Inc. | Health Care and Social Assistance | $234,900 | $236,329 | 17 | <$5M | AI Deep Dive |
| R Fralin Construction INC | Construction | $234,300 | $235,979 | 25 | $28.5M | AI Deep Dive |
| Brambleton Imports INC | Retail Trade | $232,303 | $233,406 | 19 | <$5M | AI Deep Dive |
| Security Lock & Key Inc. | Administrative and Support and Waste Management | $232,100 | $233,353 | 20 | <$5M | AI Deep Dive |
| Quick Fix Real Estate LLC | Real Estate and Rental and Leasing | $232,000 | $234,977 | 9 | <$5M | AI Deep Dive |
| Roanoker Restaurant INC | Accommodation and Food Services | $230,000 | $231,188 | 54 | $9.6M | AI Deep Dive |
| 419 West Restaurant Co. LLC | Accommodation and Food Services | $228,533 | $230,584 | 51 | $9.1M | AI Deep Dive |
| Parker Design Group, Inc. | Professional, Scientific, and Technical Services | $228,293 | $230,150 | 20 | <$5M | AI Deep Dive |
| Radiology Associates of Roanoke, PC | Health Care and Social Assistance | $228,200 | $230,476 | 10 | <$5M | AI Deep Dive |
| Extreme Design Group, Inc. | Administrative and Support and Waste Management | $225,890 | $228,776 | 30 | $6.5M | AI Deep Dive |
| Hawk Advisers INC | Finance and Insurance | $225,800 | $227,550 | 17 | $8.7M | AI Deep Dive |
| Local Office On Aging, Inc. | Other Services (except Public Administration) | $225,478 | $227,874 | 40 | $7.6M | AI Deep Dive |
| Roanoke Airport Hotel Partners LLC | Accommodation and Food Services | $225,300 | $226,770 | 27 | $8.4M | AI Deep Dive |
| Design Resource Services 360, INC | Professional, Scientific, and Technical Services | $225,000 | $226,388 | 12 | <$5M | AI Deep Dive |
| Inphase | Information | $224,900 | $226,481 | 28 | <$5M | AI Deep Dive |
| North Roanoke Assisted Living LLC | Health Care and Social Assistance | $224,750 | $226,242 | 37 | $6.3M | AI Deep Dive |
| Mountain View Lawn Care LLC | Administrative and Support and Waste Management | $223,900 | $225,523 | 46 | $10.0M | AI Deep Dive |
| Brentwood Operations, LLC | Professional, Scientific, and Technical Services | $222,482 | $226,395 | 77 | $10.8M | AI Deep Dive |
| Security Lock & Key Inc. | Administrative and Support and Waste Management | $222,000 | $223,946 | 18 | <$5M | AI Deep Dive |
| Property Management of Roanoke LLC | Real Estate and Rental and Leasing | $221,800 | $225,996 | 25 | <$5M | AI Deep Dive |