| Islands Marine Center INC | Arts, Entertainment, and Recreation | $311,700 | $313,177 | 22 | <$5M |  Research |
| Islands Marine Center INC | Arts, Entertainment, and Recreation | $299,823 | $301,154 | 22 | <$5M | Research |
| Lopez Island Building Supply | Retail Trade | $138,643 | $139,991 | 16 | <$5M | Research |
| Ascent Building Company LLC | Construction | $129,570 | $100,967 | 9 | <$5M | Research |
| North Sound Communcations 1 LLC | Construction | $120,008 | $121,280 | 11 | <$5M | Research |
| Blossom On Lopez, Inc. | Retail Trade | $87,600 | $88,070 | 12 | <$5M | Research |
| Cornerstone Healthcare Training Company, LLC | Educational Services | $85,842 | $86,650 | 12 | <$5M | Research |
| Lopez Island Family Resource Center | Health Care and Social Assistance | $85,473 | $86,438 | 19 | N/A | Research |
| Redpenny LLC DBA Haven Kitchen & Bar | Accommodation and Food Services | $77,094 | $77,835 | 5 | <$5M | Research |
| Lopez Community Land Trust | Public Administration | $75,400 | $76,216 | 3 | N/A | Research |
| Ascent Building Co. LLC | Construction | $69,000 | $69,522 | 10 | <$5M | Research |
| Parkhill Pharmacy INC | Retail Trade | $65,125 | $65,930 | 6 | <$5M | Research |
| Buffum Bros Farms INC | Construction | $63,700 | $64,012 | 7 | <$5M | Research |
| Loho | Health Care and Social Assistance | $61,358 | $62,019 | 9 | N/A | Research |
| Christine Aufderhar, Dds, Pllc | Health Care and Social Assistance | $56,920 | $57,489 | 6 | <$5M | Research |
| Tom Hilger Custom Homes Inc. | Unknown | $51,525 | $52,443 | 5 | N/A | Research |
| Red Penny LLC | Accommodation and Food Services | $51,200 | $51,824 | 11 | <$5M | Research |
| Lopez Community Land Trust | Public Administration | $46,243 | $46,398 | 9 | N/A | Research |
| Gimeto LLC | Unknown | $42,500 | $21,267 | 1 | N/A | Research |
| Lopez Children's Center | Health Care and Social Assistance | $35,178 | $35,353 | 10 | <$5M | Research |
| Lopez Children's Center | Health Care and Social Assistance | $34,546 | $34,909 | 4 | <$5M | Research |
| Ursa Minor Lopez LLC | Accommodation and Food Services | $33,462 | $33,611 | 4 | <$5M | Research |
| Lopez Ready Mix, INC | Manufacturing | $30,902 | $31,201 | 5 | <$5M | Research |
| Bakesmith INC | Manufacturing | $29,700 | $30,041 | 6 | <$5M | Research |
| Lopez Island Physical Therapy LLC | Health Care and Social Assistance | $29,152 | $29,255 | 2 | <$5M | Research |