| Noborne Preschool and Daycare Center | Health Care and Social Assistance | $5,583,400 | $56,543 | 17 | N/A |  Research |
| Shenandoah Valley Medical System Incorporated | Health Care and Social Assistance | $3,739,800 | $3,250,810 | 289 | N/A | Research |
| R M Roach & Sons INC | Transportation and Warehousing | $1,728,000 | $1,742,784 | 293 | $74.3M | Research |
| M Pizza INC | Accommodation and Food Services | $1,480,600 | $1,493,967 | 456 | $81.0M | Research |
| Eastern Panhandle Mental Health Center Inc. | Health Care and Social Assistance | $1,423,326 | $1,438,785 | 236 | N/A | Research |
| Apple Valley Cheverolet INC | Retail Trade | $1,146,500 | $1,086,323 | 132 | $33.3M | Research |
| Panhandle Builders & Excavating INC | Construction | $862,600 | $849,475 | 100 | $113.9M | Research |
| Valley Training Centers, Inc. | Public Administration | $837,300 | $844,301 | 89 | N/A | Research |
| Strategic Resolution Experts, Inc. | Professional, Scientific, and Technical Services | $774,600 | $780,131 | 51 | $5.3M | Research |
| Career Skills Institute of West Virginia, Inc. D/b/a Martins | Professional, Scientific, and Technical Services | $746,500 | $751,622 | 102 | $14.3M | Research |
| Chem-Pak INC | Manufacturing | $589,263 | $597,102 | 40 | $39.7M | Research |
| Mas Wva INC | Retail Trade | $505,800 | $479,995 | 51 | $12.9M | Research |
| Jefferson Distributing Company, Inc. | Wholesale Trade | $494,800 | $499,638 | 31 | $8.0M | Research |
| Panhandle Home Health INC | Health Care and Social Assistance | $475,395 | $477,046 | 39 | N/A | Research |
| Panhandle Home Health, INC | Health Care and Social Assistance | $475,300 | $479,274 | 39 | N/A | Research |
| D&l Weld INC | Construction | $465,000 | $467,803 | 26 | $6.0M | Research |
| D & L Weld INC | Other Services (except Public Administration) | $465,000 | $471,613 | 26 | $5.6M | Research |
| Kent Parsons Ford INC | Retail Trade | $450,000 | $455,600 | 40 | $10.1M | Research |
| Gantt's Excavating and Contracting INC | Construction | $444,448 | $447,541 | 44 | $16.5M | Research |
| Gantt's Excavating and Contracting, Inc. | Construction | $444,448 | $448,698 | 52 | $19.5M | Research |
| George S. Orr & Sons, Inc. | Agriculture, Forestry, Fishing and Hunting | $419,500 | $424,779 | 150 | $15.3M | Research |
| Bowman Murray Fulk Group | Retail Trade | $407,500 | $413,363 | 83 | $22.4M | Research |
| Martin Distributing Co INC | Manufacturing | $403,230 | $406,142 | 32 | $8.4M | Research |
| Berkeley-Mountaineer Glass and Door, Ltd | Construction | $400,900 | $405,711 | 38 | $8.8M | Research |
| Bowman Murray Fulk Group Inc. | Retail Trade | $390,000 | $395,449 | 83 | $22.4M | Research |