| Morries La Crosse Automotive LLC | Retail Trade | $349,300 | $353,065 | 36 | $9.1M | AI Deep Dive |
| The Old Crow La Crosse LLC | Accommodation and Food Services | $344,942 | $347,194 | 60 | $10.7M | AI Deep Dive |
| Schaller Jacobson, INC | Other Services (except Public Administration) | $342,800 | $344,723 | 23 | <$5M | AI Deep Dive |
| La Crosse Glass Co. Inc. | Construction | $341,460 | $343,101 | 28 | $6.5M | AI Deep Dive |
| Burrachos LLC | Accommodation and Food Services | $339,500 | $342,263 | 63 | $11.2M | AI Deep Dive |
| Cvikota Company, INC | Professional, Scientific, and Technical Services | $338,500 | $331,614 | 36 | $7.4M | AI Deep Dive |
| Five Star Telecom, Inc. | Information | $326,345 | $328,221 | 25 | <$5M | AI Deep Dive |
| John W. Moore, Dds, S.c. | Health Care and Social Assistance | $325,000 | $291,865 | 18 | <$5M | AI Deep Dive |
| Tri-State Business Machines, INC | Retail Trade | $324,500 | $326,474 | 25 | $5.4M | AI Deep Dive |
| Howie's La Crosse LLC | Accommodation and Food Services | $321,471 | $323,391 | 43 | $7.6M | AI Deep Dive |
| Midwest Garment INC | Other Services (except Public Administration) | $319,977 | $321,755 | 41 | $7.8M | AI Deep Dive |
| Midwest Garment, Inc. | Manufacturing | $319,900 | $322,050 | 41 | $14.5M | AI Deep Dive |
| Nmt Corporation | Information | $318,000 | $319,777 | 29 | <$5M | AI Deep Dive |
| Vine Street Group, LLC | Accommodation and Food Services | $317,700 | $320,215 | 60 | $10.7M | AI Deep Dive |
| Nmt Corporation | Information | $314,702 | $315,909 | 30 | $5.0M | AI Deep Dive |
| Sprout Childcare LLC | Health Care and Social Assistance | $313,500 | $141,124 | 32 | $5.2M | AI Deep Dive |
| Ftw INC | Accommodation and Food Services | $311,584 | $313,280 | 44 | $7.8M | AI Deep Dive |
| Ron Hammes Refrigeration Co. INC | Construction | $304,275 | $306,134 | 18 | $5.7M | AI Deep Dive |
| Glass Service Center Inc. | Construction | $297,700 | $300,139 | 18 | <$5M | AI Deep Dive |
| T. D. Padesky Electric, Inc. | Construction | $297,300 | $299,835 | 16 | $5.3M | AI Deep Dive |
| Ted Mannstedt & Son INC | Manufacturing | $296,357 | $297,435 | 22 | $5.4M | AI Deep Dive |
| Bob Frise Enterprises LLC | Wholesale Trade | $295,100 | $297,703 | 20 | $6.1M | AI Deep Dive |
| Intech Integrated Marketing Services LLC | Professional, Scientific, and Technical Services | $295,000 | $298,393 | 22 | <$5M | AI Deep Dive |
| Midwest Millwork and Casework, LLC | Manufacturing | $293,000 | $295,224 | 28 | $7.3M | AI Deep Dive |
| Ted Mannstedt and Son, Inc. | Manufacturing | $291,400 | $293,035 | 24 | $5.9M | AI Deep Dive |