| Patriot Chevrolet INC | Retail Trade | $498,200 | $503,182 | 48 | $12.1M | Research |
| Hopkinsville Ky Opco LLC | Health Care and Social Assistance | $497,500 | $0 | 66 | $11.2M | Research |
| Covington's Convalescent Center Inc. | Health Care and Social Assistance | $486,238 | $489,301 | 53 | $9.0M | Research |
| Convington's Convalescent Center, INC | Health Care and Social Assistance | $486,238 | $490,008 | 73 | $12.4M | Research |
| Higgins Insurance, Inc. | Finance and Insurance | $447,157 | $450,213 | 28 | $14.4M | Research |
| Staff Easy, LLC | Administrative and Support and Waste Management | $408,102 | $412,092 | 79 | $12.4M | Research |
| Sisk Nissan LLC | Retail Trade | $386,085 | $389,882 | 39 | $9.8M | Research |
| Christian Educators INC | Educational Services | $377,930 | $379,767 | 123 | N/A | Research |
| Christian Educators, Inc. | Educational Services | $377,930 | $380,911 | 123 | N/A | Research |
| Forefront Solutions Inc. | Professional, Scientific, and Technical Services | $366,200 | $368,333 | 40 | $8.3M | Research |
| Forefront Solutions INC | Professional, Scientific, and Technical Services | $362,625 | $364,761 | 38 | $7.9M | Research |
| Pennyrile Ford, INC | Retail Trade | $361,900 | $364,152 | 32 | $8.1M | Research |
| Westate Construction Inc. | Construction | $358,202 | $359,963 | 22 | $6.8M | Research |
| Westate Construction, Inc. | Construction | $358,200 | $360,916 | 22 | $6.8M | Research |
| Hopkinsville Independent School INC | Educational Services | $356,374 | $357,582 | 63 | N/A | Research |
| Hopkinsville Independent School INC | Educational Services | $356,372 | $358,372 | 63 | N/A | Research |
| Mize Machine, INC | Manufacturing | $344,500 | $346,451 | 30 | $7.9M | Research |
| Kentucky American Seeds, LLC | Wholesale Trade | $322,809 | $324,657 | 40 | $10.3M | Research |
| Therapy Staffing Specialists | Administrative and Support and Waste Management | $287,900 | $290,827 | 34 | $5.4M | Research |
| Mcafee Electric INC | Wholesale Trade | $276,192 | $277,562 | 26 | $8.0M | Research |
| Jones Bros Towing & Trucking INC | Transportation and Warehousing | $265,700 | $268,648 | 22 | <$5M | Research |
| Mcgee Pest Control, Inc. | Administrative and Support and Waste Management | $262,145 | $263,623 | 33 | $7.1M | Research |
| Richgrove Tobacco LLC | Agriculture, Forestry, Fishing and Hunting | $260,000 | $261,293 | 73 | $7.5M | Research |
| Clean Air Technology Solutions LLC | Wholesale Trade | $255,227 | $256,822 | 33 | $10.1M | Research |
| Clean Air Technology Solutions LLC | Wholesale Trade | $255,227 | $257,404 | 33 | $10.1M | Research |