| Coastal Electric Cooperative, Inc. | Utilities | $1,055,000 | $1,066,215 | 40 | N/A |  Research |
| US Waste Industries INC | Professional, Scientific, and Technical Services | $830,080 | $651,343 | 39 | <$5M | Research |
| Pioneer Boats | Manufacturing | $718,288 | $726,041 | 94 | $24.6M | Research |
| Cowboy USA | Transportation and Warehousing | $660,800 | $667,372 | 59 | $22.9M | Research |
| Cowboy USA LLC | Transportation and Warehousing | $660,800 | $667,372 | 74 | $11.2M | Research |
| Lowcountry Community Action Agency INC | Other Services (except Public Administration) | $466,044 | $469,086 | 75 | $14.3M | Research |
| Simmons Irrigation Supply INC | Wholesale Trade | $418,624 | $423,097 | 41 | $12.6M | Research |
| Crescent Daity & Beverages LLC | Agriculture, Forestry, Fishing and Hunting | $375,970 | $381,388 | 53 | $8.7M | Research |
| White Wood, Inc. | Agriculture, Forestry, Fishing and Hunting | $366,865 | $369,922 | 21 | <$5M | Research |
| B & F Mechanical LLC | Construction | $350,587 | $354,621 | 34 | $10.8M | Research |
| Colleton Preparatory Academy INC | Educational Services | $336,200 | $324,583 | 94 | N/A | Research |
| Walterboro Family Practice Associates, P.a. | Health Care and Social Assistance | $332,285 | $335,986 | 28 | $8.8M | Research |
| White Wood Inc. | Agriculture, Forestry, Fishing and Hunting | $310,314 | $312,728 | 21 | <$5M | Research |
| Naman Walterboro II LLC | Accommodation and Food Services | $288,746 | $290,262 | 44 | $13.8M | Research |
| Lowcountry Equipment Sales and Service | Manufacturing | $264,400 | $80,830 | 12 | <$5M | Research |
| General Food Store of Walterboro, INC | Wholesale Trade | $239,000 | $241,888 | 236 | $60.7M | Research |
| John Smith Jr Logging INC | Agriculture, Forestry, Fishing and Hunting | $230,100 | $231,537 | 20 | <$5M | Research |
| Carroll Enterprises LLC | Construction | $228,630 | $230,319 | 20 | $6.2M | Research |
| Mitchell Construction Company, Inc. | Construction | $224,700 | $226,716 | 11 | $12.5M | Research |
| Carroll Enterprises LLC | Construction | $219,700 | $221,452 | 18 | $5.6M | Research |
| Walterboro Motor Sales Company | Retail Trade | $214,978 | $217,151 | 20 | $5.0M | Research |
| Crosby Enterprises, Inc. | Retail Trade | $209,797 | $211,574 | 47 | $15.7M | Research |
| Priority Home Care LLC | Health Care and Social Assistance | $205,165 | $207,200 | 70 | $12.0M | Research |
| Carter Logging, Inc. | Agriculture, Forestry, Fishing and Hunting | $191,300 | $191,128 | 15 | <$5M | Research |
| Jaxco Industries INC | Administrative and Support and Waste Management | $189,900 | $206,224 | 36 | $6.8M | Research |