| White Wood 3, LLC | Agriculture, Forestry, Fishing and Hunting | $189,300 | $191,813 | 21 | <$5M | Research |
| Carter Logging Inc. | Agriculture, Forestry, Fishing and Hunting | $187,000 | $188,624 | 14 | <$5M | Research |
| Fat Jacks of Walterboro | Accommodation and Food Services | $181,000 | $182,899 | 42 | $7.5M | Research |
| Clean Management Environmental Group, Inc. | Administrative and Support and Waste Management | $180,047 | $181,936 | 11 | <$5M | Research |
| Walterboro Adult & Pediatric Medicine, LLC | Health Care and Social Assistance | $179,985 | $182,390 | 28 | $8.8M | Research |
| Paper Converters, Inc. | Manufacturing | $178,272 | $179,763 | 28 | $27.8M | Research |
| Self-Serve, Inc. | Retail Trade | $158,452 | $160,002 | 34 | $11.4M | Research |
| Ip Builders Inc. | Construction | $158,087 | $159,044 | 24 | $27.3M | Research |
| Carolina Textiles, Inc. | Wholesale Trade | $157,100 | $158,649 | 19 | $5.8M | Research |
| Wcb Logging INC | Agriculture, Forestry, Fishing and Hunting | $153,700 | $63,063 | 12 | <$5M | Research |
| The Steadman Agency, Inc. | Finance and Insurance | $152,967 | $154,356 | 11 | $5.7M | Research |
| Cook Enterprises Iii, Inc. | Accommodation and Food Services | $149,845 | $151,231 | 48 | $8.5M | Research |
| Rizer Chevrolet-Buick, Gmc, Inc. | Retail Trade | $147,167 | $168,345 | 16 | <$5M | Research |
| Advanced Pool Finishing, Inc. | Construction | $144,000 | $145,172 | 18 | $5.5M | Research |
| Westburys Hardware of Walterboro INC | Retail Trade | $142,435 | $143,578 | 36 | $7.4M | Research |
| R & D Timber Co, INC | Agriculture, Forestry, Fishing and Hunting | $140,600 | $141,794 | 13 | <$5M | Research |
| Ip Builders, Inc. | Construction | $136,456 | $137,650 | 15 | $17.1M | Research |
| Self-Serve Inc. | Retail Trade | $134,078 | $134,952 | 30 | $10.0M | Research |
| Carolina Medical Center of Walterboro, PA | Administrative and Support and Waste Management | $130,600 | $132,084 | 13 | <$5M | Research |
| Palmetto Training INC | Educational Services | $130,475 | $131,446 | 14 | <$5M | Research |
| Fat Jack's of Walterboro LLC | Accommodation and Food Services | $129,300 | $130,366 | 46 | $8.2M | Research |
| Walker Accounting & Tax Service | Professional, Scientific, and Technical Services | $129,100 | $130,158 | 13 | <$5M | Research |
| Ackerman Landscape & Irrigation, Inc. | Administrative and Support and Waste Management | $120,000 | $119,799 | 20 | <$5M | Research |
| Ackerman Landscaping and Irrigation INC | Administrative and Support and Waste Management | $118,800 | $120,105 | 20 | <$5M | Research |
| Palmetto State Forestry Services | Administrative and Support and Waste Management | $111,700 | $112,756 | 20 | <$5M | Research |