| Green Acres Baptist Church, Tyler Tx | Other Services (except Public Administration) | $1,669,472 | $1,684,775 | 222 | N/A | Research |
| M Chest Institutional Pharmacy Group LLC | Retail Trade | $1,653,117 | $1,668,454 | 153 | $26.7M | Research |
| Atlas Credit Company, INC | Finance and Insurance | $1,645,613 | $0 | 171 | $87.9M | Research |
| Charles L Heaton MD PA | Health Care and Social Assistance | $1,644,395 | $1,654,307 | 138 | $43.3M | Research |
| Fiber Network Solutions, Inc. | Manufacturing | $1,550,628 | $1,561,655 | 130 | $34.0M | Research |
| Community Access INC | Health Care and Social Assistance | $1,548,000 | $1,559,610 | 252 | $59.0M | Research |
| Mentoring Minds LP | Retail Trade | $1,516,200 | $1,522,016 | 88 | $21.0M | Research |
| Goodwill Industries of East Texas, Inc. | Retail Trade | $1,471,242 | $1,479,497 | 308 | N/A | Research |
| Goodwill Industries of East Texas | Health Care and Social Assistance | $1,471,240 | $1,482,683 | 267 | N/A | Research |
| Taste Bud, LLC | Professional, Scientific, and Technical Services | $1,471,000 | $1,480,594 | 96 | $30.6M | Research |
| Vernon E Faulconer, Inc. | Mining, Quarrying, and Oil and Gas Extraction | $1,440,798 | $1,448,802 | 79 | <$5M | Research |
| Dairy Queens of Tyler, Inc. | Accommodation and Food Services | $1,386,295 | $1,394,189 | 335 | $59.5M | Research |
| Arnold Family of Restaurants LLC | Accommodation and Food Services | $1,381,540 | $1,389,754 | 432 | $76.7M | Research |
| Mentoring Minds, L.p. | Retail Trade | $1,360,000 | $1,367,713 | 87 | $20.8M | Research |
| Reid Construction, Inc. | Construction | $1,359,787 | $1,374,631 | 100 | $113.9M | Research |
| Infinity Project Management, Inc. | Construction | $1,313,483 | $1,323,595 | 59 | $18.3M | Research |
| Infinity Project Management, Inc. | Professional, Scientific, and Technical Services | $1,313,483 | $1,325,214 | 51 | $6.3M | Research |
| Nathan Jackson, Pllc | Health Care and Social Assistance | $1,307,500 | $1,320,067 | 113 | $30.5M | Research |
| Patterson Motors of Tyler 2, Inc. | Retail Trade | $1,299,932 | $1,314,997 | 110 | $27.7M | Research |
| Texas College | Educational Services | $1,291,229 | $1,300,851 | 156 | N/A | Research |
| The Center at Grande LLC | Health Care and Social Assistance | $1,288,853 | $1,293,865 | 139 | $27.6M | Research |
| The Center at Grande LLC | Health Care and Social Assistance | $1,288,852 | $1,304,248 | 139 | $27.6M | Research |
| Vme Fabricators, Inc. | Manufacturing | $1,239,347 | $1,245,622 | 77 | $18.8M | Research |
| Level 2 Legal Solutions, LP | Professional, Scientific, and Technical Services | $1,231,300 | $1,241,253 | 83 | $22.7M | Research |
| East Texas Eye Care Associates, Pllc | Health Care and Social Assistance | $1,225,885 | $1,232,866 | 115 | $36.1M | Research |