| All Saints Episcopal School | Educational Services | $1,217,700 | $1,224,634 | 117 | N/A | Research |
| Texas College | Educational Services | $1,206,138 | $1,211,921 | 158 | N/A | Research |
| Heart to Heart Hospice of Tyler, Ltd | Health Care and Social Assistance | $1,195,168 | $1,203,633 | 117 | $19.9M | Research |
| Level 2 Legal Solutions LP | Professional, Scientific, and Technical Services | $1,170,343 | $1,180,485 | 41 | $11.2M | Research |
| Striping Technology, LP | Construction | $1,167,397 | $1,175,233 | 126 | $39.1M | Research |
| Tyler Internal Medicine Assocaites, PA | Health Care and Social Assistance | $1,148,600 | $1,157,342 | 166 | $52.1M | Research |
| Pineridge Investments,llp | Professional, Scientific, and Technical Services | $1,043,250 | $1,051,367 | 79 | $21.6M | Research |
| Hibbs-Hallmark & Company | Finance and Insurance | $1,020,000 | $1,026,460 | 84 | $37.0M | Research |
| Peltier Nissan-Pontiac | Retail Trade | $1,012,412 | $1,020,736 | 92 | $23.2M | Research |
| Legacy Pressure Control, Inc. | Mining, Quarrying, and Oil and Gas Extraction | $1,012,400 | $1,020,274 | 47 | <$5M | Research |
| Legacy Pressure Control INC | Mining, Quarrying, and Oil and Gas Extraction | $1,012,400 | $1,024,661 | 40 | <$5M | Research |
| Claims Administrative Services INC | Finance and Insurance | $995,000 | $1,001,302 | 81 | $35.6M | Research |
| Heaton Ear Nose & Throat Associates of East Texas, PA | Health Care and Social Assistance | $982,275 | $987,787 | 85 | $26.7M | Research |
| Innovative Risk Management, Inc. | Finance and Insurance | $981,362 | $988,668 | 60 | $30.8M | Research |
| Intense Wireline Solutions, LLC | Mining, Quarrying, and Oil and Gas Extraction | $979,280 | $989,644 | 37 | <$5M | Research |
| Intense Wireline Solutions Llc. | Mining, Quarrying, and Oil and Gas Extraction | $979,200 | $984,722 | 40 | <$5M | Research |
| Burton Oil Service Operations LLC | Mining, Quarrying, and Oil and Gas Extraction | $976,254 | $984,653 | 42 | <$5M | Research |
| East Texas Testing Laboratory, Inc. | Professional, Scientific, and Technical Services | $969,815 | $976,564 | 103 | $12.7M | Research |
| The Caldwell Foundation | Other Services (except Public Administration) | $962,465 | $973,013 | 100 | N/A | Research |
| Gencore Candeo Ltd | Other Services (except Public Administration) | $918,500 | $922,608 | 46 | $8.8M | Research |
| Gencore Candeo, Ltd. | Wholesale Trade | $918,500 | $924,368 | 46 | $14.1M | Research |
| Tbf Holdings Corp | Retail Trade | $912,700 | $861,573 | 74 | $18.6M | Research |
| Cardiovascular Associates of East Texas | Health Care and Social Assistance | $903,308 | $705,130 | 73 | $22.9M | Research |
| Tyler Nephrology Associates | Health Care and Social Assistance | $887,455 | $895,417 | 72 | $12.8M | Research |
| Tyler Radiology Associates | Health Care and Social Assistance | $886,721 | $896,229 | 26 | $8.2M | Research |