| The Poarch Law Firm, PC | Professional, Scientific, and Technical Services | $185,300 | $186,506 | 21 | $5.1M | AI Deep Dive |
| 8 & 10 West Main Restaurants LLC | Accommodation and Food Services | $184,359 | $186,264 | 37 | $6.6M | AI Deep Dive |
| Interstate Battery Systems of Roanoke Valley Inc. | Wholesale Trade | $180,800 | $181,870 | 15 | <$5M | AI Deep Dive |
| Whitt Carpet & Tile Service, Inc. | Construction | $180,710 | $182,869 | 15 | <$5M | AI Deep Dive |
| Routt and Associates INC | Manufacturing | $175,000 | $176,264 | 5 | <$5M | AI Deep Dive |
| Dynamic Medical LLC | Professional, Scientific, and Technical Services | $173,800 | $175,779 | 10 | <$5M | AI Deep Dive |
| Blue Ridge Diesel Injection INC | Other Services (except Public Administration) | $171,900 | $173,371 | 17 | <$5M | AI Deep Dive |
| Jayam Inc. | Accommodation and Food Services | $171,600 | $173,216 | 22 | $6.9M | AI Deep Dive |
| Blue Ridge Anesthesia Associates Inc. | Health Care and Social Assistance | $169,700 | $171,562 | 5 | <$5M | AI Deep Dive |
| Animal Care Center of Salem, P.c. | Professional, Scientific, and Technical Services | $168,705 | $150,750 | 19 | <$5M | AI Deep Dive |
| Salem Research Institute | Finance and Insurance | $164,080 | $165,746 | 20 | N/A | AI Deep Dive |
| Advanced Physical Therapy of Virginia, INC | Health Care and Social Assistance | $162,500 | $163,344 | 10 | <$5M | AI Deep Dive |
| Virginia Eastern Co LLC | Accommodation and Food Services | $160,979 | $162,007 | 30 | $9.4M | AI Deep Dive |
| Mcgrady-Lambert Electric Inc. | Construction | $160,000 | $161,153 | 20 | $6.6M | AI Deep Dive |
| Tight Lines Holdings Group INC | Manufacturing | $159,128 | $161,251 | 17 | <$5M | AI Deep Dive |
| Shenandoah Industrial Rubber Company | Manufacturing | $157,700 | $158,984 | 15 | $14.9M | AI Deep Dive |
| Stegall Inc. | Construction | $156,303 | $158,401 | 19 | $6.0M | AI Deep Dive |
| C&c Assembly, Inc. | Retail Trade | $155,500 | $0 | 14 | <$5M | AI Deep Dive |
| Blue Ridge Diesel Injection INC | Other Services (except Public Administration) | $155,432 | $156,209 | 17 | <$5M | AI Deep Dive |
| Le Tablier Bleu INC | Accommodation and Food Services | $154,168 | $155,093 | 22 | <$5M | AI Deep Dive |
| Guynn, Waddell Carroll & Lockaby, PC | Professional, Scientific, and Technical Services | $153,257 | $154,865 | 13 | <$5M | AI Deep Dive |
| Regional Conveyor Services Inc. | Construction | $151,730 | $152,840 | 13 | <$5M | AI Deep Dive |
| Regional Conveyor Services, Inc. | Construction | $151,730 | $153,127 | 13 | <$5M | AI Deep Dive |
| Noy Noy LLC | Accommodation and Food Services | $151,335 | $153,018 | 45 | $8.0M | AI Deep Dive |
| Salem Specialties INC | Manufacturing | $150,000 | $151,050 | 22 | $5.4M | AI Deep Dive |