| Mani INC | Accommodation and Food Services | $130,165 | $128,676 | 21 | $6.6M | AI Deep Dive |
| Walker Emulsions USA INC | Manufacturing | $129,522 | $131,209 | 10 | $9.9M | AI Deep Dive |
| Mack Stillinger's Body Shop, Inc. | Other Services (except Public Administration) | $126,973 | $127,773 | 12 | <$5M | AI Deep Dive |
| Xenia Hotels LLC | Accommodation and Food Services | $125,010 | $126,659 | 20 | $6.3M | AI Deep Dive |
| Murphy's Auto Glass & Lube Express LLC | Other Services (except Public Administration) | $124,300 | $125,189 | 13 | <$5M | AI Deep Dive |
| Brandrite Sign Comapny | Manufacturing | $118,933 | $119,636 | 16 | <$5M | AI Deep Dive |
| Singleton Health Center LLC | Health Care and Social Assistance | $117,668 | $118,360 | 23 | $7.2M | AI Deep Dive |
| Thompson Funeral Home Inc. | Other Services (except Public Administration) | $116,700 | $117,950 | 12 | <$5M | AI Deep Dive |
| 240 Investments LLC | Management of Companies and Enterprises | $116,666 | $117,587 | 10 | <$5M | AI Deep Dive |
| Jameson Farms, Inc. | Agriculture, Forestry, Fishing and Hunting | $110,363 | $111,718 | 7 | <$5M | AI Deep Dive |
| Garden City Enterprises, INC | Accommodation and Food Services | $109,013 | $110,045 | 43 | $7.6M | AI Deep Dive |
| Stillinger Brothers Body Shop INC | Other Services (except Public Administration) | $107,200 | $108,192 | 11 | <$5M | AI Deep Dive |
| The Wannamaker Agency INC | Finance and Insurance | $105,000 | $106,093 | 6 | <$5M | AI Deep Dive |
| Mani INC | Accommodation and Food Services | $102,640 | $102,686 | 23 | $7.2M | AI Deep Dive |
| Pioneer Farm Equipment INC | Retail Trade | $100,330 | $101,512 | 9 | <$5M | AI Deep Dive |
| Dangerfield Engineering and Surveying, LLC | Professional, Scientific, and Technical Services | $97,285 | $97,866 | 6 | <$5M | AI Deep Dive |
| Image Group of Orangeburg, Inc. | Manufacturing | $94,823 | $95,992 | 6 | $6.0M | AI Deep Dive |
| A.j. Hutto Jr. Inc. | Other Services (except Public Administration) | $94,000 | $95,064 | 12 | <$5M | AI Deep Dive |
| Lanier & Burroughs, LLC | Professional, Scientific, and Technical Services | $93,344 | $94,068 | 13 | <$5M | AI Deep Dive |
| Orangeburg Family Dentistry LLC | Health Care and Social Assistance | $92,600 | $93,389 | 12 | <$5M | AI Deep Dive |
| Edisto Engineers and Surveryors INC | Professional, Scientific, and Technical Services | $91,848 | $92,572 | 10 | <$5M | AI Deep Dive |
| Samuel L. Lambrecht D.m.d. LLC | Health Care and Social Assistance | $91,700 | $92,295 | 12 | <$5M | AI Deep Dive |
| Orangeburg Family Dentistry LLC | Health Care and Social Assistance | $91,500 | $92,120 | 10 | <$5M | AI Deep Dive |
| Cook Out-Orangeburg | Accommodation and Food Services | $91,500 | $92,603 | 30 | $5.3M | AI Deep Dive |
| Samuel L Lambrecht Dmd LLC | Health Care and Social Assistance | $90,800 | $91,780 | 12 | <$5M | AI Deep Dive |